Afadin antibody (AA 1814-1829)

Catalog No. ABIN1108256

Product Details anti-Afadin Antibody

Target: Afadin (MLLT4)

Binding Specificity: AA 1814-1829

Reactivity: Human, Rat, Mouse, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This Afadin antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Specificity: This antibody detects L-Afadin.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat, dog

Purification: Protein G

Immunogen: Peptide 1814-1829 aa of rat l-afadin

Clone: 3

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2 - 8 °C.

Target Details for Afadin

Target: Afadin (MLLT4)

Alternative Name: MLLT4 / AF6 / Afadin (MLLT4 Products)

Synonyms: MLLT4 antibody, af-6 antibody, af6 antibody, si:ch211-278j12.1 antibody, AF6 antibody, RP3-431P23.3 antibody, 5033403D15Rik antibody, Af-6 antibody, Afadin antibody, Gm314 antibody, I-afadin antibody, S-afadin antibody, Af6 antibody, afadin, adherens junction formation factor antibody, afadin, adherens junction formation factor L homeolog antibody, afadin, adherens junction formation factor a antibody, afadin antibody, AFDN antibody, afdn.L antibody, afdna antibody, LOC589923 antibody, LOC100177180 antibody, afdn antibody, Afdn antibody

Background: Afadin is an actin filament-binding protein that is involved in cell-cell adherens junctions (AJs) which directly interacts with the alpha herpus virus receptor, a member of the immunoglobulin supergene family. Afadin is colocalized with nectin at cadherin-based cell-cell adherence junctions in various tissues and cell lines. L-Afadin has been isolated as an F-actin-binding protein from rat brain. L-afadin is ubiquitously expressed and specifically localized at zonula adherens (ZA) in epithelial cells and at cell-cell adherens junctions (AJs) in non-epithelial cells. L-afadin has a splice variant, named small intestine absorptive afadin (s-afadin) which is abundantly expressed in neural tissue.Synonyms: Myeloid/lymphoid Or Mixed-lineage Leukemia Translocated To 4, Protein AF-6

Gene ID: 26955

NCBI Accession: NP_037349

UniProt: O35889

Pathways: Cell-Cell Junction Organization