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MRGBP antibody (MRG-Binding Protein) (N-Term)

Details for Product anti-MRGBP Antibody No. ABIN1108299, Supplier: Log in to see
Antigen
  • 1600027N09Rik
  • AW060503
  • C20orf20
  • c20orf20
  • C80444
  • Eaf7
  • MRG15BP
  • URCC4
  • zgc:73167
Epitope
N-Term
15
15
11
5
3
2
2
1
Reactivity
Cow (Bovine), Human, Mouse (Murine)
55
17
14
3
2
Host
Rabbit
44
8
3
Clonality
Polyclonal
Conjugate
This MRGBP antibody is un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
43
24
11
5
4
2
1
Supplier
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Immunogen The immunogen for anti-C20ORF20 antibody: synthetic peptide directed towards the N terminal of human C20ORF20
Sequence MGEAEVGGGG AAGDKGPGEA ATSPAEETVV WSPEVEVCLF HAMLGHKPVG
Cross-Reactivity (Details) Species reactivity (expected):Mouse, BovineSpecies reactivity (tested):Human
Purification Purified using Protein A affinity column
Alternative Name MRGBP (MRGBP Antibody Abstract)
Background MRGBP alos called C20orf20 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.Synonyms: C20orf20, MRG-binding protein
Gene ID 55257
NCBI Accession NP_060740
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Reconstitution Add 100 μL of distilled water to a final concentration of 1 mg/mL.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
Supplier Images
Western Blotting (WB) image for anti-MRGBP antibody (MRG-Binding Protein) (N-Term) (ABIN1108299) Transfected 293T; WB Suggested Anti-C20ORF20 Antibody Titration: 2.5ug/ml. ELISA Tite...
Background publications Cai, Jin, Tomomori-Sato, Sato, Sorokina, Parmely, Conaway, Conaway: "Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex." in: The Journal of biological chemistry, Vol. 278, Issue 44, pp. 42733-6, 2003