MUC5AC antibody

Catalog No. ABIN1108318

Product Details anti-MUC5AC Antibody

Target: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Reactivity: Mouse, Monkey, Cat, Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This MUC5AC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Purified

Immunogen: A BALB/c mouse was immunized with mucin isolated from an ovarian cyst fluid (pure endocervical type according to the Fenoglio's classification). Splenocytes were fused with mouse myeloma SP2/0 cells.

Clone: 2-12M1

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, 0.05 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MUC5AC

Target: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Alternative Name: Mucin-5AC (MUC5AC Products)

Synonyms: MUC5 antibody, TBM antibody, leB antibody, 2210005L13Rik antibody, MGM antibody, mucin 5AC, oligomeric mucus/gel-forming antibody, putative gastric mucin antibody, mucin 5, subtypes A and C, tracheobronchial/gastric antibody, mucin 2, oligomeric mucus/gel-forming antibody, MUC5AC antibody, Smp_144070 antibody, Muc5ac antibody, MUC2 antibody

Background: Mucins are high molecular weight glycoproteins that are found especially in the secretions of mucus membranes. Gastric Mucin 5AC antigen is found in columnar mucus cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon but not in normal colon. Resurgence of gastric mucin during colonic carcinogenesis is suggestive of either re-expression of the peptide core of gastric mucin in the adult colon or due to changes in the glycosylation pattern of mucin, which expose the hidden Mucin 5AC antigen.Synonyms: Gastric mucin, LeB, Lewis B blood group antigen, MUC5, MUC5AC, Major airway glycoprotein, Mucin-5 subtype AC, TBM, Tracheobronchial mucin, tracheobronchial

Gene ID: 9606

UniProt: P98088