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Myeloperoxidase antibody (FITC)

MPO Reactivity: Human FACS, IF Host: Mouse Monoclonal 266-6K2 FITC
Catalog No. ABIN1108346
  • Target See all Myeloperoxidase (MPO) Antibodies
    Myeloperoxidase (MPO)
    Reactivity
    • 173
    • 64
    • 56
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 132
    • 76
    • 1
    • 1
    • 1
    Mouse
    Clonality
    • 121
    • 90
    Monoclonal
    Conjugate
    • 92
    • 31
    • 30
    • 12
    • 10
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Myeloperoxidase antibody is conjugated to FITC
    Application
    • 124
    • 86
    • 62
    • 62
    • 32
    • 29
    • 27
    • 18
    • 16
    • 14
    • 14
    • 13
    • 10
    • 8
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    Specificity
    Clone 266.6K2 reacts with the intracellular enzyme MPO. In a study comparing anti-MPO with other myeloid-reactive monoclonal antibodies such as anti-CD13, CD14, CD15 and CD33, a higher diagnostic sensitivity and specificity was found for AML using anti-MPO. In most patients, more MPO-positive cells were detected by anti-MPO than by cytochemical staining with Sudan black and standard peroxidase. Testing by flow cytometry using a fixation and permeabilization solution on whole blood from healthy donors showed the following values expressed in terms of % of the total leukocyte count: Product code: AM39035FC-N (anti-MPO FITC) n: 10 Mean % positive: 64,06 S.D.: 5,07 % CV: 7,92
    Purification
    Affinity chromatography
    Clone
    266-6K2
    Isotype
    IgG1
    Top Product
    Discover our top product MPO Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C. Fluorochrome labelled product is photosensitive and should be protected from light.
  • Target
    Myeloperoxidase (MPO)
    Alternative Name
    Myeloperoxidase (MPO Products)
    Synonyms
    mKIAA4033 antibody, MPO antibody, LOC100335032 antibody, POX2' antibody, XPOX2' antibody, mpo antibody, mpo-A antibody, pmr-1 antibody, pmr1 antibody, pox2 antibody, xpox2 antibody, myeloperoxidase antibody, myeloperoxidase L homeolog antibody, MPO antibody, Mpo antibody, LOC100335032 antibody, mpo.L antibody
    Background
    Myeloperoxidase (MPO) is an intracellular enzyme in peripheral blood granulocytes. Anti-MPO antibodies stain promyelocytes, myelocytes, metamyelocytes and mature neutrophil granulocytes in bone marrow. Monocytes are negative or slightly positive while eosinophils and lymphocytes are negative. Anti-MPO is used for the diagnosis of AML (acute myeloid leukemia). Non-myeloid leukemia (e.g. acute lymphoblastic leukemia) is usually non-reactive with anti-MPO.Synonyms: MPO
    Gene ID
    4353
    NCBI Accession
    NP_000241
    UniProt
    P05164
    Pathways
    Chromatin Binding
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