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NCOR1 antibody (Nuclear Receptor Co-Repressor 1)

Details for Product anti-NCOR1 Antibody No. ABIN1108391, Supplier: Log in to see
Antigen
  • ncor
  • zgc:56355
  • 5730405M06Rik
  • A230020K14Rik
  • N-CoR
  • RIP13
  • Rxrip13
  • mKIAA1047
  • N-CoR1
  • TRAC1
  • hN-CoR
  • nuclear receptor co-repressor 1
  • nuclear receptor corepressor 1
  • ncor1
  • NCOR1
  • CpipJ_CPIJ002507
  • LOC100343278
  • Ncor1
Alternatives
anti-Human NCOR1 antibody for Immunohistochemistry
Reactivity
Human
98
52
25
5
2
2
2
2
1
1
1
1
1
1
Host
Mouse
84
12
3
Clonality (Clone)
Monoclonal ()
Conjugate
This NCOR1 antibody is un-conjugated
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
67
63
52
14
14
13
6
5
3
3
2
1
1
1
Options
Supplier
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Available images

Clone 7A7A9
Isotype IgG1
Specificity Recognizes Nuclear receptor co-repressor 1 (NCOR1).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name NCOR1 (NCOR1 Antibody Abstract)
Background This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.Synonyms: KIAA1047, N-CoR, N-CoR1, Nuclear receptor corepressor 1
Gene ID 9611
Pathways Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Immunohistochemistry (IHC) image for anti-NCOR1 antibody (Nuclear Receptor Co-Repressor 1) (ABIN1108391) anti-Nuclear Receptor Co-Repressor 1 (NCOR1) antibody
Western Blotting (WB) image for anti-NCOR1 antibody (Nuclear Receptor Co-Repressor 1) (ABIN1108391) anti-Nuclear Receptor Co-Repressor 1 (NCOR1) antibody (Image 2)
Background publications Axelsson, Holback, Sjögren, Gustafsson, Forsby: "Gliotoxin induces caspase-dependent neurite degeneration and calpain-mediated general cytotoxicity in differentiated human neuroblastoma SH-SY5Y cells." in: Biochemical and biophysical research communications, Vol. 345, Issue 3, pp. 1068-74, 2006 (PubMed).

Atsumi, Tomita, Kiyoi, Naoe: "Histone deacetylase 3 (HDAC3) is recruited to target promoters by PML-RARalpha as a component of the N-CoR co-repressor complex to repress transcription in vivo." in: Biochemical and biophysical research communications, Vol. 345, Issue 4, pp. 1471-80, 2006 (PubMed).

Zhang, Yoon, Wong: "JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2)." in: Molecular and cellular biology, Vol. 25, Issue 15, pp. 6404-14, 2005 (PubMed).