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Nuclear Receptor Co-Repressor 1 (NCOR1) antibody

Details for Product No. ABIN1108391, Supplier: Log in to see
Antigen
  • ncor
  • zgc:56355
  • 5730405M06Rik
  • A230020K14Rik
  • N-CoR
  • RIP13
  • Rxrip13
  • mKIAA1047
  • N-CoR1
  • TRAC1
  • hN-CoR
Reactivity
Human
91
35
19
3
Host
Mouse
79
10
3
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
60
57
50
11
9
8
3
3
2
1
1
1
Supplier
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Available images

Clone 7A7A9
Isotype IgG1
Specificity Recognizes Nuclear receptor co-repressor 1 (NCOR1).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name NCOR1 (NCOR1 Antibody Abstract)
Background This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.Synonyms: KIAA1047, N-CoR, N-CoR1, Nuclear receptor corepressor 1
Gene ID 9611
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Immunohistochemistry (IHC) image for anti-Nuclear Receptor Co-Repressor 1 (NCOR1) antibody (ABIN1108391) anti-Nuclear Receptor Co-Repressor 1 (NCOR1) antibody
Western Blotting (WB) image for anti-Nuclear Receptor Co-Repressor 1 (NCOR1) antibody (ABIN1108391) anti-Nuclear Receptor Co-Repressor 1 (NCOR1) antibody (Image 2)
Background publications Atsumi, Tomita, Kiyoi et al.: "Histone deacetylase 3 (HDAC3) is recruited to target promoters by PML-RARalpha as a component of the N-CoR co-repressor complex to repress transcription in vivo." in: Biochemical and biophysical research communications, Vol. 345, Issue 4, pp. 1471-80, 2006 (PubMed).

Axelsson, Holback, Sjögren et al.: "Gliotoxin induces caspase-dependent neurite degeneration and calpain-mediated general cytotoxicity in differentiated human neuroblastoma SH-SY5Y cells." in: Biochemical and biophysical research communications, Vol. 345, Issue 3, pp. 1068-74, 2006 (PubMed).

Zhang, Yoon, Wong: "JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2)." in: Molecular and cellular biology, Vol. 25, Issue 15, pp. 6404-14, 2005 (PubMed).