Nuclear Receptor Co-Repressor 1 (NCOR1) antibody

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Antigen
Synonyms ncor, zgc:56355, 5730405M06Rik, A230020K14Rik, N-CoR, RIP13, Rxrip13, mKIAA1047, N-CoR1, TRAC1, hN-CoR
Reactivity
Human
(90), (37), (19), (3)
Host
Mouse
(79), (10), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(63), (58), (48), (11), (9), (8), (6), (3), (2), (2), (1), (1), (1)
Pubmed 3 references available
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Quantity 0.1 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Clone 7A7A9
Isotype IgG1
Specificity Recognizes Nuclear receptor co-repressor 1 (NCOR1).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name NCOR1 (NCOR1 Antibody Abstract)
Background This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.Synonyms: KIAA1047, N-CoR, N-CoR1, Nuclear receptor corepressor 1
Gene ID 9611
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Immunohistochemistry (IHC) image for anti-Nuclear Receptor Co-Repressor 1 (NCOR1) antibody (ABIN1108391) anti-Nuclear Receptor Co-Repressor 1 (NCOR1) antibody
Western Blotting (WB) image for anti-Nuclear Receptor Co-Repressor 1 (NCOR1) antibody (ABIN1108391) anti-Nuclear Receptor Co-Repressor 1 (NCOR1) antibody (Image 2)
Background publications Atsumi, Tomita, Kiyoi et al.: "Histone deacetylase 3 (HDAC3) is recruited to target promoters by PML-RARalpha as a component of the N-CoR co-repressor complex to repress transcription in vivo." in: Biochemical and biophysical research communications, Vol. 345, Issue 4, pp. 1471-80, 2006 (PubMed).

Axelsson, Holback, Sjögren et al.: "Gliotoxin induces caspase-dependent neurite degeneration and calpain-mediated general cytotoxicity in differentiated human neuroblastoma SH-SY5Y cells." in: Biochemical and biophysical research communications, Vol. 345, Issue 3, pp. 1068-74, 2006 (PubMed).

Zhang, Yoon, Wong: "JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2)." in: Molecular and cellular biology, Vol. 25, Issue 15, pp. 6404-14, 2005 (PubMed).

Catalog No. ABIN1108391
$434.50
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