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NEFL antibody

NEFL Reactivity: Human, Rat, Pig WB, IHC (p), IHC (fro) Host: Mouse Monoclonal NF-68 unconjugated
Catalog No. ABIN1108415
  • Target See all NEFL Antibodies
    NEFL (Neurofilament, Light Polypeptide (NEFL))
    Reactivity
    • 78
    • 53
    • 43
    • 26
    • 25
    • 18
    • 4
    • 2
    • 2
    • 1
    • 1
    Human, Rat, Pig
    Host
    • 64
    • 34
    • 9
    • 1
    • 1
    • 1
    Mouse
    Clonality
    • 68
    • 42
    Monoclonal
    Conjugate
    • 71
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEFL antibody is un-conjugated
    Application
    • 62
    • 42
    • 35
    • 25
    • 19
    • 17
    • 17
    • 14
    • 13
    • 12
    • 11
    • 9
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This antibody reacts to Neurofilament L (68 kDa).
    Purification
    Affinity chromatography
    Clone
    NF-68
    Isotype
    IgG1
    Top Product
    Discover our top product NEFL Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with 1.2 % sodium acetate or neutral PBS
    Concentration
    0,1 mg/mL
    Buffer
    1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    NEFL (Neurofilament, Light Polypeptide (NEFL))
    Alternative Name
    Neurofilament L (68kDa) (NEFL Products)
    Synonyms
    NEFL antibody, nefl antibody, zgc:136626 antibody, AI847934 antibody, CMT2E antibody, NF-L antibody, NF68 antibody, Nfl antibody, CMT1F antibody, NFL antibody, XNF-L antibody, neurofilament light antibody, neurofilament, light polypeptide antibody, neurofilament, light polypeptide b antibody, neurofilament, light L homeolog antibody, NEFL antibody, neflb antibody, Nefl antibody, nefl.L antibody
    Background
    Neurofilaments are composed of 3 neuron-specific proteins with apparent molecular masses of 68 Kd (NFL), 125 kD (NFM) and 200 kD (NFH) on SDS-gel electrophoresis. And they have a role in the maturation of regenerating myelinated axons. Neurofilament 68 (NF68), also called Neurofilament rotein, Light Chain (NFL). It is one of the most abundant cytoskeletal omponents of the neuron.Mutations in this gene were reported as a cause for autosomal dominant Charcot-Marie-Tooth type 2E (CMT2E) linked to chromosome 8p21. NFL was identified repeatedly in both screenings and found to interact with Myotubularin-related 2 gene, MTMR2 in both Schwann cells and neurons.Synonyms: 68 kDa neurofilament protein, NEFL, NF-L, NF68, Neurofilament L
    Gene ID
    4747
    NCBI Accession
    NP_006149
    UniProt
    P07196
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