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GRIN2B antibody (N-Term)
GRIN2B
Reactivity: Human, Rat, Mouse
WB, IF, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GRIN2B Antibody
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Target
See all GRIN2B Antibodies
GRIN2B
(Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
Binding Specificity
All epitopes for GRIN2B antibodies
N-Term
Reactivity
All reactivities for GRIN2B antibodies
Human, Rat, Mouse
Host
All hosts for GRIN2B antibodies
Rabbit
Clonality
All clonalities for GRIN2B antibodies
Polyclonal
Conjugate
All conjugates for GRIN2B antibodies
This GRIN2B antibody is un-conjugated
Application
All applications for GRIN2B antibodies
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody detects NMDAR2B at N-term. No cross reactivity with other proteins.
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse, rat
Purification
Immunogen affinity purified
Immunogen
Peptide mapping at the N-terminus of NMDAR2B of human origin .Remarks: Sequence is identical to the related mouse sequence.
Isotype
IgG
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Discover our top product GRIN2B Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Reconstitution
1.2 % sodium acetate or neutral PBS. If 0.5 mL of PBS is used, the antibody concentration will be 100 μg/mL.
Concentration
100 ug/ml.
Buffer
50 % glycerol, 0.9 mg NaCl, 0.2 mg Na2HPO4
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target Details for GRIN2B
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Target
GRIN2B
(Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
Alternative Name
NMDAR2B (GRIN2B Products )
Synonyms
NMDAR2B antibody, GluN2B antibody, MRD6 antibody, NR2B antibody, hNR3 antibody, nmdar2b antibody, nr2b antibody, AW490526 antibody, Nmdar2b antibody, glutamate ionotropic receptor NMDA type subunit 2B antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2B L homeolog antibody, glutamate receptor, ionotropic, NMDA2B (epsilon 2) antibody, GRIN2B antibody, Grin2b antibody, grin2b.L antibody
Background
The N-methyl-D-aspartate receptor 2B, also names as GRIN2B. The sequence of the predicted 1,484-amino acid human protein is 98 % and 96 % identical to the sequences of the rat and mouse Nmdar2b proteins, respectively. Nmdar2B gene is located on mouse chromosome 6 between Rho and Ly49 centromerically and Glb telomerically. Mapping of the human NMDAR2B receptor subunit gene (GRIN2B) to chromosome 12p12 overexpression of NMDA receptor 2B (NR2B) in the forebrains of transgenic mice leads to enhanced activation of NMDA receptors, facilitating synaptic potentiation in response to stimulation at 10-100 Hz.Synonyms: GRIN2B, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, NMDA Receptor 2B
Gene ID
2904
NCBI Accession
NP_000825
UniProt
Q13224
Pathways
Response to Growth Hormone Stimulus , Synaptic Membrane , Feeding Behaviour , Regulation of long-term Neuronal Synaptic Plasticity
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