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PNPLA6 antibody (C-Term)
PNPLA6
Reactivity: Zebrafish (Danio rerio)
WB, IHC (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PNPLA6 Antibody
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Target
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PNPLA6
(Patatin-Like phospholipase Domain Containing 6 (PNPLA6))
Binding Specificity
All epitopes for PNPLA6 antibodies
AA 1323-1348, C-Term
Reactivity
All reactivities for PNPLA6 antibodies
Zebrafish (Danio rerio)
Host
All hosts for PNPLA6 antibodies
Rabbit
Clonality
All clonalities for PNPLA6 antibodies
Polyclonal
Conjugate
All conjugates for PNPLA6 antibodies
This PNPLA6 antibody is un-conjugated
Application
All applications for PNPLA6 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
Specificity
This antibody detects NTE at aa 1323-1348. No cross reactivity with other proteins.
Cross-Reactivity (Details)
Species reactivity (tested):Zebrafish
Purification
Immunogen affinity purified
Immunogen
Synthetic peptide corresponding to a sequence at the C-terminal of fish PNPLA6 (1323-1348 amino acid)
Isotype
IgG
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Reconstitution
0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Buffer
5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
Preservative
Sodium azide, Thimerosal (Merthiolate)
Precaution of Use
This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target Details for PNPLA6
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Target
PNPLA6
(Patatin-Like phospholipase Domain Containing 6 (PNPLA6))
Alternative Name
NTE (PNPLA6 Products )
Synonyms
NTE antibody, NTEMND antibody, SPG39 antibody, iPLA2delta antibody, sws antibody, AI661849 antibody, MSws antibody, Nte antibody, RGD1564611 antibody, wu:fy20f06 antibody, patatin like phospholipase domain containing 6 antibody, patatin-like phospholipase domain containing 6 antibody, PNPLA6 antibody, Pnpla6 antibody, pnpla6 antibody
Background
Patatin-like phospholipase domain containing 6 (PNPLA6), also known as Neuropathy target esterase (NTE), is a human gene. Neuropathy target esterase (NTE) is involved in neural development and is the target for neurodegeneration induced by selected organophosphorus pesticides and chemical warfare agents. The genetic or chemical reduction of Nte activity results in a neurological phenotype of hyperactivity in mammals and indicate that EOPF toxicity occurs directly through inhibition of Nte without the requirement for Nte gain of function or aging.Synonyms: Neuropathy target esterase, PNPLA6
Gene ID
10908
NCBI Accession
NP_006693
UniProt
Q8IY17
Pathways
Ribonucleoside Biosynthetic Process
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