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Occludin antibody (AA 358-504)

OCLN Reactivity: Human, Mouse, Rat, Dog WB, IF, IHC (fro) Host: Guinea Pig Polyclonal unconjugated
Catalog No. ABIN1108503
  • Target See all Occludin (OCLN) Antibodies
    Occludin (OCLN)
    Binding Specificity
    • 16
    • 16
    • 15
    • 9
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 358-504
    Reactivity
    • 102
    • 63
    • 43
    • 34
    • 18
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Human, Mouse, Rat, Dog
    Host
    • 87
    • 18
    • 2
    • 1
    Guinea Pig
    Clonality
    • 84
    • 24
    Polyclonal
    Conjugate
    • 44
    • 10
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Occludin antibody is un-conjugated
    Application
    • 86
    • 34
    • 29
    • 26
    • 26
    • 15
    • 15
    • 14
    • 12
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    The polyclonal antibody reacts with Occludin.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, Mouse, Rat, Canine.
    Purification
    Protein A Chromatography
    Immunogen
    Recombinant Human Occludin (aa 358-504)
    Isotype
    Ig Fraction
    Top Product
    Discover our top product OCLN Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS, 0.02 % Sodium Azide, 0.1 % BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store undiluted at 2-8 °C.
  • Liu, Gu, Zhu, Yuan, Zhu, Zhu, Yao, Hu, Zhang, Dicksved, Bao, Cai: "Epithelial Heat Shock Proteins Mediate the Protective Effects of Limosilactobacillus reuteri in Dextran Sulfate Sodium-Induced Colitis." in: Frontiers in immunology, Vol. 13, pp. 865982, (2022) (PubMed).

  • Target
    Occludin (OCLN)
    Alternative Name
    Occludin (OCLN Products)
    Synonyms
    AI503564 antibody, Ocl antibody, ocln antibody, oclnb antibody, tpmt antibody, OCLN antibody, wu:fd23h10 antibody, wu:fi13c01 antibody, zgc:113992 antibody, zgc:56359 antibody, BLCPMG antibody, occludin antibody, occludin S homeolog antibody, occludin a antibody, Ocln antibody, OCLN antibody, ocln.S antibody, ocln antibody, oclna antibody
    Background
    Occludin is an integral membrane protein specifically associated with tight junctions. These specialized regions of the plasma membrane prevent the diffusion of dissolved molecules between adjacent epithelial cells, seal off body cavities such as intestine or stomach lumen and prevent the diffusion of membrane proteins and glycolipids between the apical and basolateral regions of the plasma membrane. Occludin is localized at tight junctions of both epithelial and endothelial cells and is highly expressed in kidney and has not been detected in testis. On the cytoplasmic surface of occludin, a domain within the C-terminal 150 residues has been shown to bind directly to the well-characterized tight junction protein zona occludens 1 (ZO-1).Synonyms: OCLN
    Gene ID
    100506658
    NCBI Accession
    NP_001192183
    UniProt
    Q16625
    Pathways
    Cell-Cell Junction Organization, Hepatitis C
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