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PAK2 antibody (P21-Activated Kinase 2)

Details for Product anti-PAK2 Antibody No. ABIN1108567, Supplier: Log in to see
Antigen
  • 5330420P17Rik
  • A130002K10Rik
  • AI836325
  • cb422
  • D16Ertd269e
  • gamma-PAK
  • kinase
  • mKIAA4182
  • PAK-2
  • pak2
  • Pak3
  • pak65
  • PAK65
  • PAKgamma
  • pakgamma
  • PAKI
  • si:dz198m22.1
  • wu:fb71h01
  • zgc:91798
Alternatives
anti-Human PAK2 antibody for Immunohistochemistry (Paraffin-embedded Sections)
Reactivity
Human, Monkey
181
81
79
9
5
Host
Mouse
164
17
Clonality (Clone)
Monoclonal ()
Conjugate
This PAK2 antibody is un-conjugated
4
4
4
4
4
4
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
161
105
81
25
17
7
6
3
2
2
1
Supplier
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Clone 3B5
Isotype IgG1
Specificity Recognizes PAK2
Cross-Reactivity (Details) Species reactivity (tested):Human, Monkey.
Purification Ascites
Alternative Name PAK2 (PAK2 Antibody Abstract)
Background PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.Synonyms: Gamma-PAK, PAK 2, PAK gamma, PAK-2, PAK65, Serine/threonine-protein kinase PAK 2, p21-activated kinase 2, p58
Molecular Weight 61 kDa
Gene ID 5062
Research Area Cancer, Apoptosis/Necrosis, Tyrosine Kinases, Kinases/Phosphatases
Pathways MAPK Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Immunofluorescence (IF) image for anti-PAK2 antibody (P21-Activated Kinase 2) (ABIN1108567) anti-P21-Activated Kinase 2 (PAK2) antibody
Immunohistochemistry (IHC) image for anti-PAK2 antibody (P21-Activated Kinase 2) (ABIN1108567) anti-P21-Activated Kinase 2 (PAK2) antibody (Image 2)
Western Blotting (WB) image for anti-PAK2 antibody (P21-Activated Kinase 2) (ABIN1108567) anti-P21-Activated Kinase 2 (PAK2) antibody (Image 3)
Background publications Singh, Udagawa, Lee, Wassink, He, Yamamoto, Anderson, Pavitt, Asano: "Change in nutritional status modulates the abundance of critical pre-initiation intermediate complexes during translation initiation in vivo." in: Journal of molecular biology, Vol. 370, Issue 2, pp. 315-30, 2007 (PubMed).

Machuy, Campa, Thieck, Rudel: "c-Abl-binding protein interacts with p21-activated kinase 2 (PAK-2) to regulate PDGF-induced membrane ruffles." in: Journal of molecular biology, Vol. 370, Issue 4, pp. 620-32, 2007 (PubMed).

Chu, Wu, Liao, Pardo, Zhao, Li, Mendenhall, Pali, Shen, Yu, Taylor, Aversa, Molineaux, Payan, Masuda: "A novel role for p21-activated protein kinase 2 in T cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 12, pp. 7324-34, 2004 (PubMed).