anti-PAK2 antibody (P21-Activated Kinase 2)

Details for Product anti-PAK2 Antibody No. ABIN1108567
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Synonyms pak2, cb422, kinase, zgc:91798, wu:fb71h01, si:dz198m22.1, pak65, pakgamma, PAK65, PAKgamma, 5330420P17Rik, A130002K10Rik, AI836325, D16Ertd269e, PAK-2, mKIAA4182, gamma-PAK, PAKI, Pak3
Human, Monkey
(218), (119), (118), (5), (3)
(205), (13)
Clonality (Clone)
Monoclonal ()
This PAK2 antibody is un-conjugated
(6), (6), (6), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2)
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(180), (119), (78), (24), (20), (12), (5), (4), (3), (3), (1), (1)
Pubmed 3 references available
Quantity 0.1 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Clone 3B5
Isotype IgG1
Specificity Recognizes PAK2
Cross-Reactivity (Details) Species reactivity (tested):Human, Monkey.
Purification Ascites
Alternative Name PAK2 (PAK2 Antibody Abstract)
Background PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.Synonyms: Gamma-PAK, PAK 2, PAK gamma, PAK-2, PAK65, Serine/threonine-protein kinase PAK 2, p21-activated kinase 2, p58
Molecular Weight 61 kDa
Gene ID 5062
Research Area Cancer, Apoptosis/Necrosis, Tyrosine Kinases, Kinases/Phosphatases
Pathways MAPK Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Immunofluorescence (IF) image for anti-PAK2 antibody (P21-Activated Kinase 2) (ABIN1108567) anti-P21-Activated Kinase 2 (PAK2) antibody
Immunohistochemistry (IHC) image for anti-PAK2 antibody (P21-Activated Kinase 2) (ABIN1108567) anti-P21-Activated Kinase 2 (PAK2) antibody (Image 2)
Western Blotting (WB) image for anti-PAK2 antibody (P21-Activated Kinase 2) (ABIN1108567) anti-P21-Activated Kinase 2 (PAK2) antibody (Image 3)
Background publications Machuy, Campa, Thieck et al.: "c-Abl-binding protein interacts with p21-activated kinase 2 (PAK-2) to regulate PDGF-induced membrane ruffles." in: Journal of molecular biology, Vol. 370, Issue 4, pp. 620-32, 2007 (PubMed).

Singh, Udagawa, Lee et al.: "Change in nutritional status modulates the abundance of critical pre-initiation intermediate complexes during translation initiation in vivo." in: Journal of molecular biology, Vol. 370, Issue 2, pp. 315-30, 2007 (PubMed).

Chu, Wu, Liao et al.: "A novel role for p21-activated protein kinase 2 in T cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 12, pp. 7324-34, 2004 (PubMed).

Catalog No. ABIN1108567
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