P21-Activated Kinase 2 (PAK2) antibody

Details for Product No. ABIN1108567
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Antigen
Synonyms pak2, cb422, kinase, zgc:91798, wu:fb71h01, si:dz198m22.1, pak65, pakgamma, PAK65, PAKgamma, 5330420P17Rik, A130002K10Rik, AI836325, D16Ertd269e, PAK-2, mKIAA4182, gamma-PAK, PAKI, Pak3
Reactivity
Human, Monkey
(174), (109), (108), (25), (24), (12), (6), (1), (1)
Host
Mouse
(163), (12)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application
Immunofluorescence (IF), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(144), (105), (68), (25), (20), (11), (9), (5), (4), (3), (2), (1), (1)
Pubmed 3 references available
Quantity 0.1 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

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Catalog No. ABIN1108567
445.50 $
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Clone 3B5
Isotype IgG1
Specificity Recognizes PAK2
Cross-Reactivity (Details) Species reactivity (tested):Human, Monkey.
Purification Ascites
Alternative Name PAK2
Background PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.Synonyms: Gamma-PAK, PAK 2, PAK gamma, PAK-2, PAK65, Serine/threonine-protein kinase PAK 2, p21-activated kinase 2, p58
Molecular Weight 61 kDa
Gene ID 5062
Research Area Cancer, Apoptosis/Necrosis, Tyrosine Kinases, Kinases/Phosphatases
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
anti-P21-Activated Kinase 2 (PAK2) antibody anti-P21-Activated Kinase 2 (PAK2) antibody
anti-P21-Activated Kinase 2 (PAK2) antibody (2) anti-P21-Activated Kinase 2 (PAK2) antibody (Image 2)
anti-P21-Activated Kinase 2 (PAK2) antibody (3) anti-P21-Activated Kinase 2 (PAK2) antibody (Image 3)
Background publications Chu, Wu, Liao et al.: "A novel role for p21-activated protein kinase 2 in T cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 12, pp. 7324-34, 2004 (PubMed).

Singh, Udagawa, Lee et al.: "Change in nutritional status modulates the abundance of critical pre-initiation intermediate complexes during translation initiation in vivo." in: Journal of molecular biology, Vol. 370, Issue 2, pp. 315-30, 2007 (PubMed).

Machuy, Campa, Thieck et al.: "c-Abl-binding protein interacts with p21-activated kinase 2 (PAK-2) to regulate PDGF-induced membrane ruffles." in: Journal of molecular biology, Vol. 370, Issue 4, pp. 620-32, 2007 (PubMed).

Validation Images
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