POU1F1 antibody (N-Term)

Catalog No. ABIN1108700

Product Details anti-POU1F1 Antibody

Target: POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POU1F1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TPCLYKFPDH TLSHGFPPIH QPLLAEDPTA ADFKQELRRK SKLVEEPIDM

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Bovine, Pig, Dog, ChickenSpecies reactivity (tested):Human

Purification: Protein A affinity column

Immunogen: The immunogen for anti-POU1F1 antibody: synthetic peptide directed towards the N terminal of human POU1F1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 100 μL of distilled water

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term

Expiry Date: 12 months

Target Details for POU1F1

Target: POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

Alternative Name: POU1F1 (POU1F1 Products)

Synonyms: CPHD1 antibody, GHF-1 antibody, PIT1 antibody, POU1F1a antibody, Pit-1 antibody, Hmp1 antibody, Pit1 antibody, Pit1-rs1 antibody, dw antibody, dwarf antibody, GHF1 antibody, GHF1A antibody, PIT1Z antibody, PIT-1 antibody, Pit-1* antibody, pit1 antibody, pit-1 antibody, POU class 1 homeobox 1 antibody, POU domain, class 1, transcription factor 1 antibody, POU1F1 antibody, Pou1f1 antibody, pou1f1 antibody

Background: PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.Synonyms: GHF-1, GHF1, Growth hormone factor 1, PIT-1, PIT1, Pituitary-specific positive transcription factor 1

Gene ID: 5449

NCBI Accession: NP_000297

Pathways: Regulation of Carbohydrate Metabolic Process