PPP1CA antibody (Catalytic Subunit)

Catalog No. ABIN1108708

Product Details anti-PPP1CA Antibody

Target: PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))

Binding Specificity: Catalytic Subunit

Reactivity: Human, Mouse, Rat, Rabbit

Host: Mouse

Clonality: Monoclonal

Conjugate: This PPP1CA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Specificity: This antibody reacts to PPP1CA.

Purification: Affinity chromatography

Immunogen: Recombinant rabbit protein phosphatase 1alpha (PP1alpha) catalytic subunit

Clone: PP-1A

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 1.2 % sodium acetate or neutral PBS

Concentration: 0,1 mg/mL

Buffer: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PPP1CA

Target: PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))

Alternative Name: PPP1CA (PPP1CA Products)

Synonyms: PP-1A antibody, PP1A antibody, PP1alpha antibody, PPP1A antibody, Ppp1c antibody, dism2 antibody, ppp1a antibody, wu:fc04c08 antibody, wu:fc09b07 antibody, wu:fc30g11 antibody, wu:fe05h08 antibody, zgc:85729 antibody, Ppp1ca antibody, fb18b03 antibody, fd20h04 antibody, wu:fb18b03 antibody, wu:fd20h04 antibody, wu:fl22a03 antibody, zgc:55744 antibody, zgc:76940 antibody, protein phosphatase 1 catalytic subunit alpha antibody, protein phosphatase 1, catalytic subunit, alpha isoform antibody, protein phosphatase 1, catalytic subunit, alpha isozyme L homeolog antibody, protein phosphatase 1, catalytic subunit, alpha isozyme antibody, protein phosphatase 1, catalytic subunit, alpha isozyme a antibody, protein phosphatase 1, catalytic subunit, alpha isozyme b antibody, PPP1CA antibody, Ppp1ca antibody, ppp1ca.L antibody, ppp1ca antibody, ppp1caa antibody, ppp1cab antibody

Background: Protein phosphatase 1 alpha(PP1A)is one of four major serine/threonine-specific protein phosphatases which have been identified in eukaryotic cells by enzymatic methods. Phosphorylation of serine and threonine residues in proteins is a crucial step in the regulation of many cellular functions ranging from hormonal regulation to cell division and even short-term memory. Protein phosphatase-1 determined the efficacy of learning and memory by limiting acquisition and favoring memory decline. PPP1A gene is mapped to 11q13. Protein phosphatase 1 is a molecular constraint on learning and memory.Synonyms: PP-1A, PPP1A, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

Gene ID: 100009298

NCBI Accession: NP_001095176

UniProt: P62139

Pathways: M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism