Progesterone Receptor (PGR) antibody

Details for Product No. ABIN1108739
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Antigen
Synonyms PR, XPR-1, pgr, xpr-2, PGR, pg, pr, gb:dq017620, NR3C3, 9930019P03Rik, BB114106, ENSMUSG00000074510, PR-A, PR-B, LOC443444
Reactivity
Human
(400), (73), (71), (14), (12), (7), (6), (3), (2), (2), (2), (1), (1), (1)
Host
Mouse
(260), (163), (2)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(9), (9), (9), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3)
Application
Western Blotting (WB)
(283), (151), (106), (98), (66), (57), (51), (35), (30), (23), (6), (2), (1), (1), (1)
Pubmed 3 references available
Quantity 0.1 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN1108739
390.50 $
Plus shipping costs $45.00

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  • +1 404 474 4654
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Clone 8A11H1
Isotype IgG1
Specificity Recognizes Progesterone Receptor (PGR)
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name Progesterone Receptor
Background This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined.Synonyms: NR3C3, Nuclear Receptor Subfamily 3 Group C Member 3, PGR, PR
Gene ID 5241
Research Area Cancer, Endocrine system, Transcription Factors, Hormones, Receptors
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
anti-Progesterone Receptor (PGR) antibody anti-Progesterone Receptor (PGR) antibody
Background publications Tung, Abdel-Hafiz, Shen et al.: "Progesterone receptors (PR)-B and -A regulate transcription by different mechanisms: AF-3 exerts regulatory control over coactivator binding to PR-B." in: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 11, pp. 2656-70, 2006 (PubMed).

Buser, Gass-Handel, Wyszomierski et al.: "Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 21, Issue 1, pp. 106-25, 2006 (PubMed).

Yin, Lin, Cheng et al.: "Progesterone receptor regulates Bcl-2 gene expression through direct binding to its promoter region in uterine leiomyoma cells." in: The Journal of clinical endocrinology and metabolism, Vol. 92, Issue 11, pp. 4459-66, 2007 (PubMed).

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