RAP1A antibody

Catalog No. ABIN1108827

Product Details anti-RAP1A Antibody

Target: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RAP1A antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificity: Recognizes RAP1A

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Purified

Clone: 5F8

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, 0.05 % Sodium Azide, 0.5 % protein stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for RAP1A

Target: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Alternative Name: RAP1A (RAP1A Products)

Background: The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50 % amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.Synonyms: C21KG, GTP-binding protein smg p21A, KREV-1, KREV1, RAP-1A, Ras-related protein Krev-1, Ras-related protein Rap-1A

Molecular Weight: 21 kDa

Gene ID: 5906

Pathways: TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor