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s100 antibody (S100 Calcium Binding Protein A1)

Details for Product anti-S100A1 Antibody No. ABIN1108918, Supplier: Log in to see
Antigen
  • S100a1
  • S100A1
  • DKFZp468K0511
  • S100
  • S100-alpha
  • S100A
  • AI266795
  • S100a
  • NEF
  • S100-B
  • S100beta
Reactivity
Human
217
90
70
64
14
10
2
1
1
1
1
1
1
1
Host
Mouse
155
115
10
2
1
Clonality (Clone)
Monoclonal ()
Conjugate
This s100 antibody is un-conjugated
14
13
7
5
5
5
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
153
122
110
80
36
21
16
13
10
7
4
1
1
1
1
1
1
Supplier
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Clone 2C8B8
Isotype IgG1
Specificity Recognizes S100 calcium binding protein A1 (S100-alpha/ S100A1).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name S100A1 (S100A1 Antibody Abstract)
Background S100 calcium binding protein A1 (S100-alpha/ S100A1), it is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.Synonyms: S-100 protein alpha chain, S-100 protein subunit alpha, S100 alpha, S100 calcium-binding protein A1, S100-A1, S100A
Gene ID 6271
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Buffer 0.03 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-s100 antibody (S100 Calcium Binding Protein A1) (ABIN1108918) anti-S100 Calcium Binding Protein A1 (S100A1) antibody
Immunohistochemistry (IHC) image for anti-s100 antibody (S100 Calcium Binding Protein A1) (ABIN1108918) anti-S100 Calcium Binding Protein A1 (S100A1) antibody (Image 2)
Background publications Koenig, Wojcieszyn, Weeks et al.: "Expression of S100a, vimentin, NSE, and melan A/MART-1 in seven canine melanoma cells lines and twenty-nine retrospective cases of canine melanoma." in: Veterinary pathology, Vol. 38, Issue 4, pp. 427-35, 2001 (PubMed).

Hoyaux, Decaestecker, Heizmann et al.: "S100 proteins in Corpora amylacea from normal human brain." in: Brain research, Vol. 867, Issue 1-2, pp. 280-8, 2000 (PubMed).

Pingerelli, Mizukami, Wagner et al.: "Investigation of the Ca2(+)-dependent interaction of trifluoperazine with S100a: a 19F NMR and circular dichroism study." in: Journal of protein chemistry, Vol. 9, Issue 2, pp. 169-75, 1990 (PubMed).