S100 Calcium Binding Protein A1 (S100A1) antibody

Details for Product No. ABIN1108918
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Antigen
Synonyms S100a1, S100A1, DKFZp468K0511, S100, S100-alpha, S100A, AI266795, S100a, NEF, S100-B, S100beta
Reactivity
Human
(142), (78), (42), (38), (16), (4), (2), (1)
Host
Mouse
(109), (84), (5), (1), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(8), (5), (2), (1), (1), (1)
Application
Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(104), (88), (81), (65), (29), (29), (18), (16), (11), (6), (6), (5), (3), (1), (1), (1), (1)
Pubmed 3 references available
Quantity 0.1 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN1108918
390.50 $
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Clone 2C8B8
Isotype IgG1
Specificity Recognizes S100 calcium binding protein A1 (S100-alpha/ S100A1).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name S100A1
Background S100 calcium binding protein A1 (S100-alpha/ S100A1), it is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.Synonyms: S-100 protein alpha chain, S-100 protein subunit alpha, S100 alpha, S100 calcium-binding protein A1, S100-A1, S100A
Gene ID 6271
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Buffer 0.03 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
anti-S100 Calcium Binding Protein A1 (S100A1) antibody anti-S100 Calcium Binding Protein A1 (S100A1) antibody
anti-S100 Calcium Binding Protein A1 (S100A1) antibody (2) anti-S100 Calcium Binding Protein A1 (S100A1) antibody (Image 2)
Background publications Pingerelli, Mizukami, Wagner et al.: "Investigation of the Ca2(+)-dependent interaction of trifluoperazine with S100a: a 19F NMR and circular dichroism study." in: Journal of protein chemistry, Vol. 9, Issue 2, pp. 169-75, 1990 (PubMed).

Hoyaux, Decaestecker, Heizmann et al.: "S100 proteins in Corpora amylacea from normal human brain." in: Brain research, Vol. 867, Issue 1-2, pp. 280-8, 2000 (PubMed).

Koenig, Wojcieszyn, Weeks et al.: "Expression of S100a, vimentin, NSE, and melan A/MART-1 in seven canine melanoma cells lines and twenty-nine retrospective cases of canine melanoma." in: Veterinary pathology, Vol. 38, Issue 4, pp. 427-35, 2001 (PubMed).

Validation Images
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