AIMP1 antibody (Internal Region)

Catalog No. ABIN1108958

Product Details anti-AIMP1 Antibody

Target: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Binding Specificity: AA 137-149, Internal Region

Reactivity: Human, Rat, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This AIMP1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-KQQSIAGSAD SKP

Cross-Reactivity (Details): Species reactivity (expected):Canine (Dog), Pig.
Species reactivity (tested):Human.

Purification: Affinity Chromatography

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_004748.2, NP_001135888.1. Genename: AIMP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Target Details for AIMP1

Target: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Alternative Name: SCYE1 / EMAP2 (AIMP1 Products)

Synonyms: EMAP2 antibody, EMAPII antibody, HLD3 antibody, SCYE1 antibody, p43 antibody, wu:fa95a05 antibody, zgc:154081 antibody, AIMP1 antibody, 9830137A06Rik antibody, AIMP1/p43 antibody, Emap2 antibody, Scye1 antibody, scye1 antibody, aminoacyl tRNA synthetase complex interacting multifunctional protein 1 antibody, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 antibody, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 S homeolog antibody, AIMP1 antibody, aimp1 antibody, Aimp1 antibody, aimp1.S antibody

Background: EMAPII is an approximate 20 kDa apoptosis-induced pro-inflammatory cytokine, produced by enzymatic cleavage of a precursor identical to the p43 auxiliary component of the aminoacyl-tRNA synthetase complex. Studies have shown the ability of EMAPII to induce monocyte and neutrophil chemotaxis, stimulate tissue factor-dependent coaggulation, elevate the expression of E- and P-selectins and tumour necrosis factor receptor-1, induce stress-related apoptosis in endothelial cells, inhibit angiogenesis of vascular beds, and suppress primary and metastatic tumour growth.Synonyms: AIMP1, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, EMAP-2, EMAP-II, Endothelial monocyte-activating polypeptide 2, Endothelial monocyte-activating polypeptide II, Multisynthase complex auxiliary component p43, Small inducible cytokine subfamily E member 1

Gene ID: 9255

NCBI Accession: NP_001135887