SCG3 antibody (C-Term)

Catalog No. ABIN1108963

Product Details anti-SCG3 Antibody

Target: SCG3 (Secretogranin III (SCG3))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCG3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody detects Secretogranin-3 (SCG3) at C-term. No cross reactivity with other proteins.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Immunogen affinity purified

Immunogen: Synthetic peptide corresponding to a sequence near the C-terminal of human SCG3 .Remarks: Sequence is different from the related mouse and rat sequence by single amino acid

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for SCG3

Target: SCG3 (Secretogranin III (SCG3))

Alternative Name: Secretogranin-3 (SCG3) (SCG3 Products)

Synonyms: SgIII antibody, scg3-A antibody, zgc:73236 antibody, sgiii antibody, DKFZp459J1919 antibody, SGIII antibody, 1B1075 antibody, AI385542 antibody, Chgd antibody, secretogranin III L homeolog antibody, secretogranin III antibody, scg3.L antibody, scg3 antibody, SCG3 antibody, Scg3 antibody

Background: SCG3 (secretogranin III) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Genetic variations in the SCG3 gene may influence the risk of obesity through possible regulation of hypothalamic neuropeptide secretion. SCG3 was the only gene within a haplotype block that contained rs3764220. SCG3 mRNA and immunoreactivity were detected in the paraventricular nucleus, lateral hypothalamic area, and arcuate nucleus, and the protein coexisted with orexin, melanin-concentrating hormone, neuropeptide Y, and proopiomelanocortin. SCG3 formed a granule-like structure together with these neuropeptides.Synonyms: Secretogranin III, Sg-III, SgIII

Gene ID: 29106

NCBI Accession: NP_037375

UniProt: Q8WXD2