SETDB2 antibody (N-Term)

Catalog No. ABIN1108989

Product Details anti-SETDB2 Antibody

Target: SETDB2 (SET Domain, Bifurcated 2 (SETDB2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Cow, Dog, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This SETDB2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-QRRHAKTNSH SSALH

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Canine (Dog), Bovine, Porcine.
Species reactivity (tested):Human.

Purification: Affinity Chromatography

Immunogen: Synthetic Peptide (C-QRRHAKTNSHSSALH) from the C- or N- Terminus of the protein sequence according to NP_114121.2, NP_001153780.1. Genename: SETDB2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SETDB2

Target: SETDB2 (SET Domain, Bifurcated 2 (SETDB2))

Alternative Name: SETDB2 / CLLD8 (SETDB2 Products)

Synonyms: C13orf4 antibody, CLLD8 antibody, CLLL8 antibody, KMT1F antibody, Clld8 antibody, Gm293 antibody, SET domain bifurcated 2 antibody, SET domain, bifurcated 2 antibody, SETDB2 antibody, Setdb2 antibody

Background: Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity.Synonyms: C13orf4, Chronic lymphocytic leukemia deletion region gene 8 protein, Histone-lysine N-methyltransferase SETDB2, KMT1F, Lysine N-methyltransferase 1F, SET domain bifurcated 2

Molecular Weight: 81.9 kDa (NP_114121.2).

Gene ID: 9606