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SOX2 antibody (SRY (Sex Determining Region Y)-Box 2)

Details for Product anti-SOX2 Antibody No. ABIN1109109, Supplier: Log in to see
Antigen
  • Qscn6
  • Qsox
  • Sox-2
  • rSOx
  • ANOP3
  • MCOPS3
  • RGD1565646
  • SRY-box2
  • Xsox-2
  • anop3
  • mcops3
  • sox-2
  • lcc
  • ysb
  • cb236
  • wu:fb83g04
  • wu:fc14d07
  • zgc:65860
  • zgc:77389
  • SRY (sex determining region Y)-box 2
  • quiescin Q6 sulfhydryl oxidase 1
  • SRY-box containing gene 2
  • LOC100231711
  • Qsox1
  • SOX2
  • Sox2
  • sox2
Alternatives
anti-Human SOX2 antibody for Western Blotting
Reactivity
Human
434
151
78
30
26
19
16
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11
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10
10
7
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3
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2
1
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1
Host
Mouse
290
152
7
Clonality (Clone)
Monoclonal ()
Conjugate
This SOX2 antibody is un-conjugated
21
19
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11
11
8
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6
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6
4
4
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3
3
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2
1
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1
Application
Western Blotting (WB)
316
170
131
131
118
95
88
56
15
7
6
6
6
4
2
2
2
1
1
1
1
1
1
Options
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Clone 10F10C9
Isotype IgG1
Specificity Recognizes SRY (sex determining region Y)-box 2 (SOX2).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name SOX2 (SOX2 Antibody Abstract)
Background This protein is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).Synonyms: ANOP3, MCOPS3, SRY (sex determining region Y)-box 2, SRY-box 2, SRY-related HMG-box gene 2, Transcription factor SOX-2
Gene ID 6657
Research Area Embryogenesis, Embryonic stem cells, Reproduction, Transcription Factors, Neural Stem Cell marker
Pathways Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Western Blotting (WB) image for anti-SOX2 antibody (SRY (Sex Determining Region Y)-Box 2) (ABIN1109109) anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody
Background publications Park, Zhao, West, Yabuuchi, Huo, Ince, Lerou, Lensch, Daley: "Reprogramming of human somatic cells to pluripotency with defined factors." in: Nature, Vol. 451, Issue 7175, pp. 141-6, 2008 (PubMed).

Baer, Eriksson, Faull, Rees, Curtis: "Sox-2 is expressed by glial and progenitor cells and Pax-6 is expressed by neuroblasts in the human subventricular zone." in: Experimental neurology, Vol. 204, Issue 2, pp. 828-31, 2007 (PubMed).