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SOX2 antibody (SRY (Sex Determining Region Y)-Box 2)

Details for Product anti-SOX2 Antibody No. ABIN1109110, Supplier: Log in to see
Antigen
  • ANOP3
  • anop3
  • cb236
  • lcc
  • MCOPS3
  • mcops3
  • Qscn6
  • Qsox
  • RGD1565646
  • rSOx
  • sox-2
  • Sox-2
  • SRY-box2
  • wu:fb83g04
  • wu:fc14d07
  • Xsox-2
  • ysb
  • zgc:65860
  • zgc:77389
Reactivity
Human
309
87
44
13
9
7
7
5
5
4
4
3
2
1
1
1
Host
Mouse
249
62
7
4
Clonality (Clone)
Monoclonal ()
Conjugate
This SOX2 antibody is un-conjugated
17
13
12
11
11
11
3
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
208
145
62
59
54
44
38
33
12
7
6
5
4
3
2
2
2
2
1
1
1
Supplier
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Available images

Clone 10F10
Isotype IgG1
Specificity Recognizes SOX2
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name SOX2 (SOX2 Antibody Abstract)
Background Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.Synonyms: ANOP3, MCOPS3, SRY (sex determining region Y)-box 2, SRY-box 2, SRY-related HMG-box gene 2, Transcription factor SOX-2
Molecular Weight 34 kDa
Gene ID 20674
Research Area Embryogenesis, Embryonic stem cells, Reproduction, Transcription Factors, Neural Stem Cell marker
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Western Blotting (WB) image for anti-SOX2 antibody (SRY (Sex Determining Region Y)-Box 2) (ABIN1109110) anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody
Immunohistochemistry (IHC) image for anti-SOX2 antibody (SRY (Sex Determining Region Y)-Box 2) (ABIN1109110) anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody (Image 2)
Immunofluorescence (IF) image for anti-SOX2 antibody (SRY (Sex Determining Region Y)-Box 2) (ABIN1109110) anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody (Image 3)
Background publications Dabdoub, Puligilla, Jones, Fritzsch, Cheah, Pevny, Kelley: "Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 47, pp. 18396-401, 2008

Qin, Gan, Shao, Wang, Li, Wang, He, Xu, Zhang, Kou, Zeng, Sheng, Esteban, Gao, Pei: "Mouse meningiocytes express Sox2 and yield high efficiency of chimeras after nuclear reprogramming with exogenous factors." in: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33730-5, 2008

Tay, Zhang, Thomson, Lim, Rigoutsos: "MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation." in: Nature, Vol. 455, Issue 7216, pp. 1124-8, 2008