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SOX2 antibody (SRY (Sex Determining Region Y)-Box 2)

Details for Product anti-SOX2 Antibody No. ABIN1109110, Supplier: Log in to see
Antigen
  • Qscn6
  • Qsox
  • Sox-2
  • rSOx
  • ANOP3
  • MCOPS3
  • RGD1565646
  • SRY-box2
  • Xsox-2
  • anop3
  • mcops3
  • sox-2
  • lcc
  • ysb
  • cb236
  • wu:fb83g04
  • wu:fc14d07
  • zgc:65860
  • zgc:77389
  • SRY (sex determining region Y)-box 2
  • quiescin Q6 sulfhydryl oxidase 1
  • SRY-box containing gene 2
  • LOC100231711
  • Qsox1
  • SOX2
  • Sox2
  • sox2
Alternatives
anti-Human SOX2 antibody for Western Blotting
Reactivity
Human
434
151
78
30
26
19
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10
7
4
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2
2
1
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1
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1
Host
Mouse
290
152
7
Clonality (Clone)
Monoclonal ()
Conjugate
This SOX2 antibody is un-conjugated
21
19
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16
11
11
8
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6
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4
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3
3
2
2
1
1
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1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
316
170
130
130
118
95
88
56
15
7
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4
2
2
2
1
1
1
1
1
1
Options
Supplier
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Available images

Clone 10F10
Isotype IgG1
Specificity Recognizes SOX2
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name SOX2 (SOX2 Antibody Abstract)
Background Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.Synonyms: ANOP3, MCOPS3, SRY (sex determining region Y)-box 2, SRY-box 2, SRY-related HMG-box gene 2, Transcription factor SOX-2
Molecular Weight 34 kDa
Gene ID 20674
Research Area Embryogenesis, Embryonic stem cells, Reproduction, Transcription Factors, Neural Stem Cell marker
Pathways Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Western Blotting (WB) image for anti-SOX2 antibody (SRY (Sex Determining Region Y)-Box 2) (ABIN1109110) anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody
Immunohistochemistry (IHC) image for anti-SOX2 antibody (SRY (Sex Determining Region Y)-Box 2) (ABIN1109110) anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody (Image 2)
Immunofluorescence (IF) image for anti-SOX2 antibody (SRY (Sex Determining Region Y)-Box 2) (ABIN1109110) anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody (Image 3)
Background publications Dabdoub, Puligilla, Jones, Fritzsch, Cheah, Pevny, Kelley: "Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 47, pp. 18396-401, 2008 (PubMed).

Qin, Gan, Shao, Wang, Li, Wang, He, Xu, Zhang, Kou, Zeng, Sheng, Esteban, Gao, Pei: "Mouse meningiocytes express Sox2 and yield high efficiency of chimeras after nuclear reprogramming with exogenous factors." in: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33730-5, 2008 (PubMed).

Tay, Zhang, Thomson, Lim, Rigoutsos: "MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation." in: Nature, Vol. 455, Issue 7216, pp. 1124-8, 2008 (PubMed).