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Thymus High Mobility Group Box Protein (TOX) (N-Term) antibody

Details for Product No. ABIN1109284, Supplier: Log in to see
Antigen
  • TOX1
  • 1700007F02Rik
Epitope
N-Term
9
1
Reactivity
Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)
14
7
3
2
2
2
Host
Rabbit
14
3
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
Application
Western Blotting (WB)
14
3
3
3
2
2
2
1
1
1
Supplier
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Immunogen The immunogen for anti-TOX antibody: synthetic peptide directed towards the N terminal of human TOX.
Sequence CLDPYYCNKF DGENMYMSMT EPSQDYVPAS QSYPGPSLES EDFNIPPITP
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Dog, Rat, Bovine, ChickenSpecies reactivity (tested):Human
Purification Purified using peptide immunoaffinity column
Alternative Name TOX (TOX Antibody Abstract)
Background Some high-mobility group (HMG) box proteins (e.g., LEF1) contain a single HMG box motif and bind DNA in a sequence-specific manner, while other members of this family (e.g., HMG1) have multiple HMG boxes and bind DNA in a sequence-independent but structure-dependent manner. All HMG box proteins are able to induce a sharp bend in DNA. TOX contains a single HMG box motif.Some high-mobility group (HMG) box proteins (e.g., LEF1) contain a single HMG box motif and bind DNA in a sequence-specific manner, while other members of this family (e.g., HMG1) have multiple HMG boxes and bind DNA in a sequence-independent but structure-dependent manner. All HMG box proteins are able to induce a sharp bend in DNA. TOX contains a single HMG box motif.[supplied by OMIM].Synonyms: KIAA0808, Thymocyte selection-associated high mobility group box protein TOX, Thymus high mobility group box protein TOX
Gene ID 9760
NCBI Accession NP_055544
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Reconstitution Add 50 μL of distilled water to a final concentration of 1 mg/mL.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
Supplier Images
Western Blotting (WB) image for anti-Thymus High Mobility Group Box Protein (TOX) (N-Term) antibody (ABIN1109284) Human Jurkat; WB Suggested Anti-TOX Antibody Titration: 0.2-1 ug/ml. Positive Control...
Background publications Aliahmad, OFlaherty, Han et al.: "TOX provides a link between calcineurin activation and CD8 lineage commitment." in: The Journal of experimental medicine, Vol. 199, Issue 8, pp. 1089-99, 2004 (PubMed).