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ITK antibody (IL2-Inducible T-Cell Kinase)

Details for Product anti-ITK Antibody No. ABIN1109424, Supplier: Log in to see
Antigen
  • Emt
  • EMT
  • LPFS1
  • LYK
  • PSCTK2
  • Tcsk
  • Tsk
Alternatives
anti-Human ITK antibody for Western Blotting
Reactivity
Human
99
23
17
3
1
1
1
1
Host
Mouse
58
29
22
Clonality (Clone)
Monoclonal ()
Conjugate
This ITK antibody is un-conjugated
7
6
6
6
6
6
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
91
72
6
6
5
5
4
3
2
1
1
Supplier
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Available images

Clone 5G6
Isotype IgG1
Specificity This antibody reacts to ITK.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name Tyrosine-Protein Kinase ITK/TSK (ITK Antibody Abstract)
Background This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.Synonyms: EMT, Kinase EMT, LYK, T-cell-specific kinase, Tyrosine-protein kinase Lyk
Molecular Weight 72 kDa
Gene ID 3702
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Flow Cytometry (FACS) image for anti-ITK antibody (IL2-Inducible T-Cell Kinase) (ABIN1109424) anti-IL2-Inducible T-Cell Kinase (ITK) antibody
Immunofluorescence (IF) image for anti-ITK antibody (IL2-Inducible T-Cell Kinase) (ABIN1109424) anti-IL2-Inducible T-Cell Kinase (ITK) antibody (Image 2)
Western Blotting (WB) image for anti-ITK antibody (IL2-Inducible T-Cell Kinase) (ABIN1109424) anti-IL2-Inducible T-Cell Kinase (ITK) antibody (Image 3)
Western Blotting (WB) image for anti-ITK antibody (IL2-Inducible T-Cell Kinase) (ABIN1109424) anti-IL2-Inducible T-Cell Kinase (ITK) antibody (Image 4)
ELISA image for anti-ITK antibody (IL2-Inducible T-Cell Kinase) (ABIN1109424) anti-IL2-Inducible T-Cell Kinase (ITK) antibody (Image 5)
Background publications Huck, Feyen, Niehues, Rüschendorf, Hübner, Laws, Telieps, Knapp, Wacker, Meindl, Jumaa, Borkhardt: "Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." in: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, 2009