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ITK antibody (IL2-Inducible T-Cell Kinase)

Details for Product anti-ITK Antibody No. ABIN1109424, Supplier: Login to see New
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Antigen
Synonyms Emt, Tcsk, Tsk, EMT, LPFS1, LYK, PSCTK2
Alternatives
Reactivity
Human
(105), (24), (21), (3), (1), (1), (1), (1)
Host
Mouse
(61), (32), (24)
Clonality (Clone)
Monoclonal ()
Conjugate
This ITK antibody is un-conjugated
(7), (6), (6), (6), (6), (5), (1)
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(98), (72), (8), (6), (5), (5), (4), (3), (2), (2), (1)
Pubmed 1 reference available
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Quantity 0.1 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Clone 5G6
Isotype IgG1
Specificity This antibody reacts to ITK.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name Tyrosine-Protein Kinase ITK/TSK (ITK Antibody Abstract)
Background This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.Synonyms: EMT, Kinase EMT, LYK, T-cell-specific kinase, Tyrosine-protein kinase Lyk
Molecular Weight 72 kDa
Gene ID 3702
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Flow Cytometry (FACS) image for anti-ITK antibody (IL2-Inducible T-Cell Kinase) (ABIN1109424) anti-IL2-Inducible T-Cell Kinase (ITK) antibody
Immunofluorescence (IF) image for anti-ITK antibody (IL2-Inducible T-Cell Kinase) (ABIN1109424) anti-IL2-Inducible T-Cell Kinase (ITK) antibody (Image 2)
Western Blotting (WB) image for anti-ITK antibody (IL2-Inducible T-Cell Kinase) (ABIN1109424) anti-IL2-Inducible T-Cell Kinase (ITK) antibody (Image 3)
Western Blotting (WB) image for anti-ITK antibody (IL2-Inducible T-Cell Kinase) (ABIN1109424) anti-IL2-Inducible T-Cell Kinase (ITK) antibody (Image 4)
ELISA image for anti-ITK antibody (IL2-Inducible T-Cell Kinase) (ABIN1109424) anti-IL2-Inducible T-Cell Kinase (ITK) antibody (Image 5)
Background publications Huck, Feyen, Niehues et al.: "Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." in: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, 2009 (PubMed).

Catalog No. ABIN1109424
$423.50
Plus shipping costs $45.00

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