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Ubiquitin antibody

Details for Product No. ABIN1109441, Supplier: Log in to see
Antigen
  • CG11624
  • DmUb
  • DmUbi-p63E
  • Dmel\\CG11624
  • Ub
  • Ubi-P63e
  • Ubi-p
  • Ubi63E
  • Ubi63p
  • Ubip
  • Ubiq
  • Ubp
  • ubi
  • ubi-p63E
  • ubi63E
  • CG18282
  • CG32744
  • CR32744
  • DmUbi-p5E
  • Dmel\\CG32744
  • ubiquitin
  • si:dz180g5.5
  • si:busm1-180g5.5
  • LOC100194618
  • UBIQ
  • Ubiquitin
  • LOC100282068
  • polyubiquitin-B-like
  • Ubiquitin-63E
  • Ubiquitin-5E
  • transmembrane and ubiquitin-like domain containing 2
  • polyubiquitin
  • polyubiquitin containing 7 ubiquitin monomers
  • Ubiquitin
  • ubiquitin
  • ubiquitin B
  • LOC100716362
  • Ubi-p63E
  • Ubi-p5E
  • tmub2
  • LOC100194618
  • LOC100282068
  • LOC100190766
  • LOC100135798
  • UBB
Reactivity
Human
274
202
139
133
40
32
30
29
24
24
24
23
23
22
22
20
10
8
5
5
3
2
2
2
2
2
1
1
1
1
Host
Mouse
211
174
6
4
3
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
15
12
10
10
10
9
5
5
5
5
5
5
5
5
5
5
5
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
315
187
137
91
91
81
45
35
25
12
11
10
8
4
3
2
1
Options
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Clone 3C12
Isotype IgG1
Specificity Recognizes UBB
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Purified
Background This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.Synonyms: Polyubiquitin-B, UBB
Molecular Weight 26 kDa
Gene ID 7314
Research Area Neurology, Proteolysis / Ubiquitin, Alzheimer's Disease, Proteases, Amino Acids
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, 0.05 % Sodium Azide, 0.5 % protein stabilizer
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
ELISA image for anti-Ubiquitin antibody (ABIN1109441) anti-Ubiquitin antibody
Flow Cytometry (FACS) image for anti-Ubiquitin antibody (ABIN1109441) anti-Ubiquitin antibody (Image 2)
Western Blotting (WB) image for anti-Ubiquitin antibody (ABIN1109441) anti-Ubiquitin antibody (Image 3)
Western Blotting (WB) image for anti-Ubiquitin antibody (ABIN1109441) anti-Ubiquitin antibody (Image 4)
Background publications Choudhary, Kumar, Gnad, Nielsen, Rehman, Walther, Olsen, Mann: "Lysine acetylation targets protein complexes and co-regulates major cellular functions." in: Science (New York, N.Y.), Vol. 325, Issue 5942, pp. 834-40, 2009 (PubMed).