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CHMP3 antibody

CHMP3 Reactivity: Human WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1109497
  • Target See all CHMP3 Antibodies
    CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))
    Reactivity
    • 21
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 19
    • 2
    Rabbit
    Clonality
    • 20
    • 1
    Polyclonal
    Conjugate
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHMP3 antibody is un-conjugated
    Application
    • 14
    • 7
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    Reacts with 25 kDa hVps24.
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography on Protein A
    Immunogen
    Synthetic peptide derived from internal domain of Human Vps24 protein
    Top Product
    Discover our top product CHMP3 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore in distilled water.
    Buffer
    0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))
    Alternative Name
    VPS24 (CHMP3 Products)
    Synonyms
    CG9779 antibody, Dmel\\CG9779 antibody, Vps24 antibody, dvps24 antibody, vps24 antibody, VPS24 antibody, CHMP3 antibody, GB15107 antibody, wu:fb47g01 antibody, zgc:76972 antibody, NEDF antibody, 25.1 antibody, 4921505F14Rik antibody, 9130011K15Rik antibody, CGI-49 antibody, D6Ertd286e antibody, Vacuolar protein sorting 24 antibody, charged multivesicular body protein 3 antibody, SNF7 family protein antibody, hypothetical protein antibody, neuroendocrine differentiation factor, putative antibody, charged multivesicular body protein 3 S homeolog antibody, Vps24 antibody, chmp3 antibody, VPS24.2 antibody, CpipJ_CPIJ004098 antibody, PGTG_02107 antibody, LOC5569267 antibody, Smp_032150 antibody, CHMP3 antibody, LOC410607 antibody, Chmp3 antibody, chmp3.S antibody
    Background
    The charged multivesicular body proteins, commonly designated CHMPs, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins. CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, II or III complexes. These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), as well as required for the formation of these bodies. CHMP3, also known as Vps24, associates directly with CHMP2 and CHMP4 for the disassembly of ESCRT-III complex in an ATP-dependent manner. During HIV-1 infection, the virus uses the ESCRT-III complex to mediate budding and exocytosis of viral proteins. Overexpression of CHMP3 strongly inhibits HIV-1 release. CHMP3 is expressed in brain, skeletal muscle, heart, lung, kidney and liver.Synonyms: CGI-149, CHMP3, Charged multivesicular body protein 3, Chromatin-modifying protein 3, NEDF, Neuroendocrine differentiation factor, Vacuolar protein-sorting-associated protein 24
    Gene ID
    51652
    NCBI Accession
    NP_001005753
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