WD Repeat Domain 5 (WDR5) antibody

Details for Product No. ABIN1109506
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Antigen
Synonyms zgc:56591, zgc:76895, wu:fk47f04, wdr5-a, MGC80538, wdr5-b, MGC81485, big-3, swd3, xwdr5, BIG-3, SWD3, 2410008O07Rik, AA408785, AA960360, Big, Big-3
Reactivity
Human
(51), (8), (4)
Host
Mouse
(36), (19), (1), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(3), (3), (2), (2), (2), (2)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(51), (33), (9), (7), (5), (3), (3), (2), (1)
Pubmed 1 reference available
Quantity 0.1 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN1109506
390.50 $
Plus shipping costs $45.00

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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Clone 7B11
Isotype IgG2b
Specificity Recognizes WDR5 / BIG3
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name WDR5 / BIG3
Background WD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.Synonyms: BIG-3, BMP2-induced 3-kb gene protein, WD repeat-containing protein 5
Molecular Weight 36.6 kDa
Gene ID 11091
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
anti-WD Repeat Domain 5 (WDR5) antibody anti-WD Repeat Domain 5 (WDR5) antibody
Background publications Patel, Vought, Dharmarajan et al.: "A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex." in: The Journal of biological chemistry, Vol. 283, Issue 47, pp. 32162-75, 2008 (PubMed).

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