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Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1) (N-Term) antibody

Details for Product No. ABIN1109509, Supplier: Log in to see
Antigen
  • WHSC1
  • fc12c04
  • wu:fc12c04
  • wu:fi20c01
  • si:rp71-77d7.2
  • whs
  • nsd2
  • trx5
  • mmset
  • reiibp
  • MMSET
  • NSD2
  • REIIBP
  • TRX5
  • WHS
  • RGD1565590
  • 5830445G22Rik
  • 9430010A17Rik
  • AW555663
  • C130020C13Rik
  • D030027O06Rik
  • D930023B08Rik
  • Whsc1l
  • mKIAA1090
Epitope
N-Term
17
9
8
6
3
1
1
1
1
Reactivity
Chicken, Human, Mouse (Murine), Rat (Rattus)
36
5
2
2
Host
Rabbit
32
4
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
33
15
4
3
2
2
2
2
1
Supplier
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Immunogen The immunogen for anti-WHSC1 antibody: synthetic peptide directed towards the N terminal of human WHSC1
Sequence KYNVGDLVWS KVSGYPWWPC MVSADPLLHS YTKLKGQKKS ARQYHVQFFG
Specificity This antibody will detect Isoform 1 (152 kDa), Isoform 3 (72 kDa), Isoform 5 (69 kDa) and Isoform 6 (53 kDa) because the immunogenic sequence is missing in Isoform 2, 4 and 7.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat, ChickenSpecies reactivity (tested):Human
Purification Purified using peptide immunoaffinity column
Alternative Name WHSC1 (WHSC1 Antibody Abstract)
Background WHSC1 encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4.Synonyms: KIAA1090, MMSET, Multiple myeloma SET domain-containing protein, NSD2, Nuclear SET domain-containing protein 2, Probable histone-lysine N-methyltransferase NSD2, TRX5, Trithorax-5, Wolf-Hirschhorn syndrome candidate 1 protein
Gene ID 7468
NCBI Accession NP_055734
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Reconstitution Add 50 μL of distilled water to a final concentration of 1 mg/mL.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
Supplier Images
Western Blotting (WB) image for anti-Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1) (N-Term) antibody (ABIN1109509) Human HepG2; WB Suggested Anti-WHSC1 Antibody Titration: 0.2-1 ug/ml. Positive Contro...
Background publications Santra, Zhan, Tian et al.: "A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript." in: Blood, Vol. 101, Issue 6, pp. 2374-6, 2003 (PubMed).