Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1) (N-Term) antibody

Details for Product No. ABIN1109509
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Antigen
Synonyms
WHSC1, fc12c04, wu:fc12c04, wu:fi20c01, si:rp71-77d7.2, whs, nsd2, trx5, mmset, reiibp, MMSET, NSD2, REIIBP, TRX5, WHS, RGD1565590, 5830445G22Rik, 9430010A17Rik, AW555663, C130020C13Rik, D030027O06Rik ... show more
WHSC1, fc12c04, wu:fc12c04, wu:fi20c01, si:rp71-77d7.2, whs, nsd2, trx5, mmset, reiibp, MMSET, NSD2, REIIBP, TRX5, WHS, RGD1565590, 5830445G22Rik, 9430010A17Rik, AW555663, C130020C13Rik, D030027O06Rik, D930023B08Rik, Whsc1l, mKIAA1090 show less
Epitope
N-Term
(8), (7), (3), (2), (1), (1), (1), (1)
Reactivity
Chicken, Human, Mouse (Murine), Rat (Rattus)
(18), (2), (2), (2)
Host
Rabbit
(15), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(15), (8), (2), (1), (1), (1)
Pubmed 1 reference available
Quantity 50 µg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN1109509
401.50 $
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Immunogen The immunogen for anti-WHSC1 antibody: synthetic peptide directed towards the N terminal of human WHSC1
Sequence KYNVGDLVWS KVSGYPWWPC MVSADPLLHS YTKLKGQKKS ARQYHVQFFG
Specificity This antibody will detect Isoform 1 (152 kDa), Isoform 3 (72 kDa), Isoform 5 (69 kDa) and Isoform 6 (53 kDa) because the immunogenic sequence is missing in Isoform 2, 4 and 7.
Purification Purified using peptide immunoaffinity column
Alternative Name WHSC1
Background WHSC1 encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4.
Alternate names: KIAA1090, MMSET, Multiple myeloma SET domain-containing protein, NSD2, Nuclear SET domain-containing protein 2, Probable histone-lysine N-methyltransferase NSD2, TRX5, Trithorax-5, Wolf-Hirschhorn syndrome candidate 1 protein
Gene ID 7468
NCBI Accession NP_055734
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water to a final concentration of 1 mg/mL.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store lyophilized at 2-8°C or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for up to one month or in aliquots at -20°C long term.
Expiry Date 12 months
Background publications Santra, Zhan, Tian et al.: "A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript." in: Blood, Vol. 101, Issue 6, pp. 2374-6, 2003 (PubMed).

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