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XAF1 antibody (C-Term)
XAF1
Reactivity: Human, Mouse, Rat
WB, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-XAF1 Antibody
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Target
See all XAF1 Antibodies
XAF1
(XiAP Associated Factor 1 (XAF1))
Binding Specificity
All epitopes for XAF1 antibodies
C-Term
Reactivity
All reactivities for XAF1 antibodies
Human, Mouse, Rat
Host
All hosts for XAF1 antibodies
Rabbit
Clonality
All clonalities for XAF1 antibodies
Polyclonal
Conjugate
All conjugates for XAF1 antibodies
This XAF1 antibody is un-conjugated
Application
All applications for XAF1 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody detects XAF1 (C-term). No cross reactivity with other proteins.
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse, rat
Purification
Immunogen affinity purified
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminal of human XAF1 .Remarks: Sequence is identical to the related rat and mouse sequence.
Isotype
IgG
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Discover our top product XAF1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Reconstitution
0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Buffer
5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
Preservative
Sodium azide, Thimerosal (Merthiolate)
Precaution of Use
This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target Details for XAF1
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Target
XAF1
(XiAP Associated Factor 1 (XAF1))
Alternative Name
XAF1 (XAF1 Products )
Synonyms
BIRC4BP antibody, HSXIAPAF1 antibody, XIAPAF1 antibody, Fbxo39 antibody, XIAP associated factor 1 antibody, xaf1 antibody, XAF1 antibody, Xaf1 antibody
Background
XIAP associated factor-1, also known as XAF1, is a human gene. X-linked inhibitor of apoptosis (XIAP,MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells. And alteration in XAF1 and XIAP RNA expression levels may lead to increased apoptotic resistance and proliferation due to unregulated XIAP function in cancer cells.Synonyms: BIRC4-binding protein, BIRC4BP, XIAP-associated factor 1, XIAPAF1
Gene ID
54739
NCBI Accession
NP_059993
UniProt
Q6GPH4
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