KEL antibody

Catalog No. ABIN111374

Product Details anti-KEL Antibody

Target: KEL (Kell Blood Group, Metallo-Endopeptidase (KEL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KEL antibody is un-conjugated

Application: Aggregation (AGG), Enzyme Immunoassay (EIA), Haemagglutination (H), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody recognises CD238, also known as the kell blood group antigen Kpbc. The kell blood group antigens are carried on a 93 kDa erythrocyte membrane glycoprotein. In haemaggulation tests, BRIC203 reacts with Kp (a-b+) but not Kp (a+b-). In addition this antibody will agglutinate Kp (a+b-c+) and Kp (a-b-c+) erythrocytes but not react with Ko Erythrocytes.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein G

Immunogen: Human Erythrocytes. Spleen cells from immunised Balb/c were fused with cells of a myeloma cell line.

Clone: BRIC203

Isotype: IgG1

Application Details

Application Notes: Immunoprecipitation. Haemagglutination.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Tris Buffered Glycine, pH 7.8 containing 0.09 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for KEL

Target: KEL (Kell Blood Group, Metallo-Endopeptidase (KEL))

Alternative Name: CD238 / KEL (KEL Products)

Synonyms: CD238 antibody, Ece3 antibody, ECE3 antibody, Kell blood group antibody, Kell blood group, metallo-endopeptidase antibody, Kel antibody, KEL antibody

Background: Blood Group Kell Antigen is a type II transmembrane glycoprotein. The Kell glycoprotein links to the XK membrane protein, that carries the Kx antigen via a single disulfide bond. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases.Synonyms: Kell blood group glycoprotein

Gene ID: 3792

NCBI Accession: NP_000411

UniProt: P23276