Abl-Interactor 1 (ABI1) antibody

Details for Product No. ABIN111459
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms
ABA INSENSITIVE 1, AtABI1, F20B18.190, F20B18_190, PROTEIN PHOSPHATASE 2C ABI1, abi1, wu:fc66g09, wu:fk56a10, zgc:73174, MGC84356, ABI1, abi-1, e3b1, nap1bp, ssh3bp, ssh3bp1, abi-2, abi2b, aip-1, ablb ... show more
ABA INSENSITIVE 1, AtABI1, F20B18.190, F20B18_190, PROTEIN PHOSPHATASE 2C ABI1, abi1, wu:fc66g09, wu:fk56a10, zgc:73174, MGC84356, ABI1, abi-1, e3b1, nap1bp, ssh3bp, ssh3bp1, abi-2, abi2b, aip-1, ablbp3, argbpia, argbpib, ssh3bp2, wu:fe48a10, zgc:153534, DKFZp469P1319, ABI-1, ABLBP4, E3B1, NAP1BP, SSH3BP, SSH3BP1, NAP1, Ssh3bp1, E3b1 show less
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(72), (33), (31), (12), (12), (1), (1)
Host
Mouse
(70), (4)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(54), (27), (17), (17), (12), (10), (9), (9), (7), (6), (3), (2)
Pubmed 7 references available
Quantity 0.2 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN111459
1,281.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Recombinant Hssh3bp1 (human spectrin SH3 domain binding protein 1)
Clone 4-00E-002
Isotype IgG2b
Specificity This antibody was developed against the spectrin SH3 domain binding protein Hssh3bp1 (3).
Purification Protein A Chromatography
Alternative Name ABI1 / SSH3BP1
Background Hssh3bp1 is a marker of macropinocytic vesicles and a potential regulator of macropinocytosis (2). The gene encoding Hssh3bp1 has a role as a tumor suppressor gene which is inactivated during prostate tumorigenesis (1).Synonyms: ABI1, Abelson interactor 1, Abi-1, Abl interactor 1, Abl-binding protein 4, AblBP4, Eps8 SH3 domain-binding protein, Nap1-binding protein, SSH3BP1, Spectrin SH3 domain-binding protein 1, e3B1
Gene ID 10006
NCBI Accession NP_001012768
UniProt Q8IZP0
Application Notes Western blot: 1/1,000-1/2,000. Immunofluorescence: 1/100-1/500. Immunohistochemistry: 1/40-1/100. Formalin-fixed, paraffin-embedded sections andfrozen sections. For optimal staining, sections should be pre-treated for antigenunmasking.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS without preservatives
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Background publications Lamaze, Schmid: "The emergence of clathrin-independent pinocytic pathways." in: Current opinion in cell biology, Vol. 7, Issue 4, pp. 573-80, 1996 (PubMed).

Bennett, Gilligan: "The spectrin-based membrane skeleton and micron-scale organization of the plasma membrane." in: Annual review of cell biology, Vol. 9, pp. 27-66, 1994 (PubMed).

Ziemnicka-Kotula, Xu, Gu et al.: "Identification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton." in: The Journal of biological chemistry, Vol. 273, Issue 22, pp. 13681-92, 1998 (PubMed).

De Matteis, Morrow: "Spectrin tethers and mesh in the biosynthetic pathway." in: Journal of cell science, Vol. 113 ( Pt 13), pp. 2331-43, 2000 (PubMed).

Xu, Ziemnicka, Merz et al.: "Human spectrin Src homology 3 domain binding protein 1 regulates macropinocytosis in NIH 3T3 cells." in: Journal of cell science, Vol. 113 Pt 21, pp. 3805-14, 2000 (PubMed).

Macoska, Xu, Ziemnicka et al.: "Loss of expression of human spectrin src homology domain binding protein 1 is associated with 10p loss in human prostatic adenocarcinoma." in: Neoplasia (New York, N.Y.), Vol. 3, Issue 2, pp. 99-104, 2001 (PubMed).

Swanson, Watts: "Macropinocytosis." in: Trends in cell biology, Vol. 5, Issue 11, pp. 424-8, 2004 (PubMed).

Validation Images
Did you look for something else?
back to top