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Insulin antibody

INS Reactivity: Human IHC (p), IHC (fro), RIA, EIA Host: Mouse Monoclonal C-PEP-01 unconjugated
Catalog No. ABIN111475
  • Target See all Insulin (INS) Antibodies
    Insulin (INS)
    Reactivity
    • 190
    • 106
    • 91
    • 76
    • 70
    • 40
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 137
    • 86
    • 13
    • 2
    • 1
    • 1
    Mouse
    Clonality
    • 144
    • 98
    Monoclonal
    Conjugate
    • 121
    • 20
    • 15
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
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    • 4
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    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    This Insulin antibody is un-conjugated
    Application
    • 83
    • 74
    • 67
    • 67
    • 66
    • 55
    • 47
    • 39
    • 26
    • 24
    • 21
    • 17
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    • 11
    • 9
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    • 6
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    • 1
    • 1
    • 1
    • 1
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    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Radioimmunoassay (RIA), Enzyme Immunoassay (EIA)
    Specificity
    This antibody clone C-PEP-01 reacts specifically with C-peptide of Proinsulin. No cross-reactivity with Insulin or other peptide hormones or proteins was observed.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Also reacts to: Proinsulin
    Purification
    Precipitation Methods.
    Immunogen
    Human C-peptide conjugated to Bovine Serum Albumin
    Clone
    C-PEP-01
    Isotype
    IgG1
    Top Product
    Discover our top product INS Primary Antibody
  • Application Notes
    ELISA. RIA. Immunocytochemistry. Immunohistochemistry on Paraffin Sections (2-5 μg/mL). Pretreatment of paraffin sectionswith 0.1 % trypsin in PBS for 30 min at 37 °C is recommended. Positive Control: Human pancreas (islets of Langerhans)According to customer information this antibody does not work in Western blotting.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH ~7.4, 15 mM Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • Target
    Insulin (INS)
    Alternative Name
    Insulin (INS Products)
    Synonyms
    IDDM2 antibody, ILPR antibody, IRDN antibody, MODY10 antibody, ins1 antibody, xins antibody, ins1-a antibody, Insulin antibody, AA986540 antibody, Ins-2 antibody, InsII antibody, Mody antibody, Mody4 antibody, proinsulin antibody, zgc:109842 antibody, igf2-A antibody, ins antibody, ins-a antibody, ins-b antibody, insulin antibody, insulin precursor antibody, insulin II antibody, preproinsulin antibody, insulin L homeolog antibody, insulin S homeolog antibody, INS antibody, INS-IGF2 antibody, ins antibody, Ins antibody, PIN antibody, Ins2 antibody, ins.L antibody, ins.S antibody
    Background
    Proinsulin consists of the three parts: C-peptide and two long strands of amino acids (alpha and beta chains, later become linked together to form the Insulin molecule). From every molecule of Proinsulin, one molecule of Insulin plus one molecule of C-peptide are produced. C-peptide is released into the blood stream in equal amounts to Insulin.Synonyms: INS
    Gene ID
    3630
    NCBI Accession
    NP_000198
    UniProt
    P01308
    Pathways
    NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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