C1q antibody
| Antigen |
|
| Clonality |
Monoclonal (3R9-2) |
|
Host
|
|
|
Reactivity
|
|
|
Application
|
 Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Radioimmunoassay (RIA), Western Blotting (WB)
|
| Catalog no. |
ABIN111797 |
| Quantity |
0.1 mg (1.1 mg/ml) (Variants) |
| Price |
830.00 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 7 to 10 Business Days |
|
Characteristics
|
Synonyms: Complement C1q, Complement 1q
|
|
Swiss-Prot
|
P02745
|
|
Immunogen
|
Highly purified human C1q
|
|
Isotype
|
IgG1 (Matching secondary antibodies)
|
|
Clone
|
3R9-2
|
|
Description
|
C1q is a sub-component of the first complement component C1, which is formed by theinteraction of C1q with the tetramer C1s-C1r-C1r-C1s. C1q is a member of a family of soluble collagen-like proteins and is composed of threebasic subunits termed C1QA, C1QB and C1QC which asociate in the proportion 6 A-Bsubunits (52, 750 Da) and 3 C-C subunits (47,600 Da), to form whole C1q (459,300 Da). C1qbinds to IgG and IgM immune complexes, this activates C1r and C1s, which are also boundto C1q and so initiates the classical pathway of complement activation.
|
|
Specificity
|
Raised against purified C1q Protein. the antibody is specific for the globular head domain. Species: Human. Others not tested.
|
|
Application Notes
|
Immunohistochemistry on Frozen sections. Western Blot. Flow cytometry. ELISA. RIA. Hemagglutination. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
|
|
Concentration
|
1.1 mg/ml
|
|
Buffer
|
Borate buffered saline, pH 8.4, 0.09% sodium azide
|
|
Storage
|
The antibody can be shipped at 2-8°C. Store (in aliquots) at -20°C only. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
|
|
Research Area
|
Neurology, Innate Immunity, Complement Factors
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "C1q", type "Antibodies"
|
Hosts
|
Sheep (7), Mouse (3), Goat (2), Rabbit (2)
|
|
Reactivities
|
Human (14), Mouse (Murine) (1), Rat (Rattus) (1)
|
|
Applications
|
Enzyme Immunoassay (EIA) (6), Immunodiffusion (ID) (4), Immunohistochemistry (Frozen Sections) (IHC (fro)) (4), Immunoprecipitation (IP) (3), Western Blotting (WB) (3), Immunofluorescence (IF) (2), ELISA (1), Flow Cytometry (FACS) (1), Functional Studies (Func) (1), Radioimmunoassay (RIA) (1)
|
|
Conjugates
|
FITC (3), HRP (2)
|
