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ICAM1 antibody (Biotin)

ICAM1 Reactivity: Human WB, FACS, IHC (p), IHC (fro) Host: Mouse Monoclonal 1304 Biotin
Catalog No. ABIN111935
  • Target See all ICAM1 Antibodies
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    Reactivity
    • 208
    • 80
    • 38
    • 7
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Human
    Host
    • 120
    • 107
    • 27
    • 4
    • 1
    • 1
    • 1
    Mouse
    Clonality
    • 139
    • 119
    • 1
    Monoclonal
    Conjugate
    • 121
    • 26
    • 22
    • 18
    • 9
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ICAM1 antibody is conjugated to Biotin
    Application
    • 165
    • 149
    • 62
    • 61
    • 45
    • 40
    • 34
    • 34
    • 28
    • 28
    • 25
    • 20
    • 12
    • 10
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Protein A Chromatography.
    Immunogen
    Cultured Human endothelial cells
    Clone
    1304
    Isotype
    IgG2a
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    Discover our top product ICAM1 Primary Antibody
  • Application Notes
    Immunohistochemistry on Frozen Sections: 0.25 μg/mL (1/800). Immunohistochemistry on Paraffin Sections: 2 μg/mL (1/100). Proteinase K pretreatmentfor antigen retrieval is recommended. Suggested Positive Control: Human tonsil. Has been described to work in FACS and Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with 0.5 mL distilled water.
    Concentration
    0.2 mg/mL
    Buffer
    Stock Solution contains PBS, pH 7.2 with 0.01 % Thimerosal as preservative and 1 % BSA as stabilizer.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    This product is photosensitive and should be protected from light
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted Prior to and following reconstitution at 2-8 °C. DO NOT FREEZE.
  • Target
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    Alternative Name
    CD54 / ICAM1 (ICAM1 Products)
    Synonyms
    BB2 antibody, CD54 antibody, P3.58 antibody, Icam-1 antibody, Ly-47 antibody, MALA-2 antibody, ICAM antibody, ICAM-1 antibody, ICAM1 antibody, intercellular adhesion molecule 1 antibody, intercellular adhesion molecule-1 antibody, ICAM1 antibody, Icam1 antibody, ICAM-1 antibody
    Target Type
    Viral Protein
    Background
    ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor
    Gene ID
    9606
    UniProt
    P05362
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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