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Cytokeratin 13 antibody

KRT13 Reactivity: Human, Rat, Cow WB, IHC (p), IF, IHC (fro) Host: Mouse Monoclonal Ks13-1 unconjugated
Catalog No. ABIN112324
  • Target See all Cytokeratin 13 (KRT13) Antibodies
    Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))
    Reactivity
    • 76
    • 38
    • 32
    • 11
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Cow
    Host
    • 58
    • 21
    • 1
    • 1
    Mouse
    Clonality
    • 50
    • 31
    Monoclonal
    Conjugate
    • 52
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cytokeratin 13 antibody is un-conjugated
    Application
    • 60
    • 32
    • 18
    • 17
    • 16
    • 13
    • 9
    • 7
    • 7
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    Ks 13.1 represents an excellent marker to discriminate non-cornified squamous epithelia from those of different origin. Polypeptide reacting: Mr 54 000 polypeptide human keratin K13 (formerly designated cytokeratin13, with minor affinity to keratins K14, Mr 50 000, and K16, Mr 48 000). Tumors specifically detected: several squamous cell carcinomas, e.g. cervix carcinoma, transitional cell carcinoma of the bladder, craniopharyngioma.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, Bovine and Rat.
    Purification
    Protein A affinity chromatography
    Immunogen
    Keratin K13 of Mr 54.000 purified from human esophagus.
    Clone
    Ks13-1
    Isotype
    IgG1
    Top Product
    Discover our top product KRT13 Primary Antibody
  • Application Notes
    Immunofluorescence. Immunohistochemistry on frozen and paraffin sections: 1: 10, protease pretreatmentimproves the performance of this excellent marker in immunohisto-chemistry: 1/10 withPBS, pH 7.4. Western Blot. Incubation time: 1h at RT, extended with parafin.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore in 1 mL dist. water.
    Buffer
    PBS, pH 7.4, 0.09 % Sodium Azide, 0.5 % BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))
    Alternative Name
    Cytokeratin 13 (KRT13 Products)
    Synonyms
    krt13 antibody, CK13 antibody, K13 antibody, Ka13 antibody, Krt-1.13 antibody, Krt1-13 antibody, ck13 antibody, k13 antibody, keratin 24 antibody, keratin 13 antibody, keratin 13, type I S homeolog antibody, krt24 antibody, KRT13 antibody, Krt13 antibody, krt13.S antibody, k13 antibody
    Background
    Cytokeratin 13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus.Synonyms: CK-13, CK13, K13, KRT-13, KRT13, Keratin type I cytoskeletal 13, Keratin-13
    Gene ID
    3860
    NCBI Accession
    NP_002265
    UniProt
    P13646
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