Laminin, alpha 2 (LAMA2) antibody

Antigen: Laminin, alpha 2 (LAMA2)

Synonyms: LAMM, LAMA2

Clonality: Monoclonal (5H2)

Host: Mouse

Reactivity: Human, Monkey, Rabbit

Application: Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)

Catalog no.: ABIN112343

Additional Information

Characteristics: Synonyms: Laminin M chain, Merosin heavy chain, LAMA2, LAMM, Laminin subunit alpha-2

Alternative name: Laminin alpha 2

Swiss-Prot: P24043

Immunogen: Purified Human Merosin.

Format: Ascites

Isotype: IgG  (Matching secondary antibodies)

Clone: 5H2

Description: Laminins are trimeric basement glycoproteins consisting of three nonidenticalmultidomain chains (alpha, beta and gamma) each encoded by a distinct gene. Thealpha-2 chain is a subunit of Laminin-2 and Laminin-4, which are widely expressed in thebasement membrane of skeletal muscle and peripheral nerves. Laminins are thought tomediate cell attachment, migration, proliferation and differentiation with otherextracellular matrix components.

Specificity: This antibody reacts with the 80 kD fragment of the M-chain of Human Laminin alpha-2,originally known as Merosin. Species Reactivity: Tested: Human. Reacts with Monkey and Rabbit.

Application Details

Application Notes: ELISA: 1/25000-1/100000. Immunoprecipitation. Western Blot. Immunohistochemistry on Frozen Sections: 1/2000-1/10000 (Acetone is recommended).8µm fixed cryostat muscle sections have been used, with an HRP conjugated secondaryantibody for detection. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Restrictions: For Research Use only