TRIM21 antibody

Catalog No. ABIN112979

Product Details anti-TRIM21 Antibody

Target: TRIM21 (Tripartite Motif Containing 21 (TRIM21))

Reactivity: Human

Host: Human

Clonality: Polyclonal

Conjugate: This TRIM21 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), Immunodiffusion (ID)

Specificity: Shows only the SSA precipitate band when tested using double immunodiffusion against bovine spleen extract. Specificity is verified by identity of precipitation with CDC-AF reference serum. Titer will vary with test system, however, undiluted antibody shows a strong SSA precipitate band. Exhibits no reactivity at a dilution of 1:100 when tested against purified SSB, Scl-70, Sm, Sm/RNP, and Jo-1 antigens in an ELISA system designed to detect all IgG subclasses.

Purification: The human plasma is delipidized and defibrinated, then the immunoglobulin fraction is precipitated and collected.

Application Details

Application Notes: ELISA. Immunodiffusion.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with 2 mL deionized water.

Buffer: 0.01 M phosphate, 0.13 M NaCl. pH 7.2 with 0.02 % sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: 4 °C

Storage Comment: Stable for one year after reconstitution when stored at 2-8 °C. For extended storage keep in aliquots at -20 °C.

Expiry Date: 12 months

Target Details for TRIM21

Target: TRIM21 (Tripartite Motif Containing 21 (TRIM21))

Alternative Name: SS-A / Ro52 / TRIM21 (TRIM21 Products)

Synonyms: RNF81 antibody, RO52 antibody, SSA antibody, SSA1 antibody, Ro52 antibody, Ssa1 antibody, tripartite motif containing 21 antibody, tripartite motif-containing 21 antibody, TRIM21 antibody, Trim21 antibody

Background: Synonyms: 52 kDa Ro protein, RO52 SSA2, RO60, Ro 60 kDa autoantigen, RoRNP, SSA1, Sjoegren syndrome type A antigen

Gene ID: 6737

NCBI Accession: NP_003132

UniProt: P19474