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Apolipoprotein E (APOE) antibody

Details for Product No. ABIN112982
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Antigen
Synonyms AD2, LDLCQ5, LPG, AI255918, APOEA, Apo-E, ad2, apoprotein, im:7036787, wu:fb69a05, zgc:110064, apoe
Reactivity
Mouse (Murine)
(175), (38), (30), (4), (3), (1)
Host
Rabbit
(99), (65), (46)
Clonality
Polyclonal
Conjugate
Un-conjugated
(12), (7), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application
Immunodiffusion (ID), Western Blotting (WB)
(150), (124), (42), (42), (20), (18), (12), (10), (8), (7), (7), (6), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
Quantity 1 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN112982
308.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Purified Mouse Apolipoprotein E from pooled mouse plasma high and very low density lipoproteins
Specificity This antibody detects Apo E. Species Reactivity: Tested: Mouse, human (extremely low)
Purification Serum
Alternative Name Apolipoprotein E (Apo E)
Background Apolipoprotein E is essential for the normal catabolism of triglyceride rich lipoprotein constituents. The apolipoprotein E gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in Apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Mutations in the APOE gene confer susceptibility to Alzheimer's disease by affecting amyloid-beta deposition.
Alternate names: Apo-E, ApoE
Gene ID 11816
NCBI Accession NP_033826.2
UniProt P08226
Research Area Metabolism
Application Notes Radial immunodiffusion assay (1: 40)Immuno double-diffusion. Rocket IEP. Western blot (1: 500 - 1: 1,000). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid repeated freezing and thawing. Dilute only prior to immediate use.
Storage -20 °C
Storage Comment Store the antibody undiluted (in aliquots) at -20°C.
Expiry Date 12 months
Background publications Hayhurst, Lee, Lambert et al.: "Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis." in: Molecular and cellular biology, Vol. 21, Issue 4, pp. 1393-403, 2001 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN112982
308.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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