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Calcitonin-Related Polypeptide alpha (CALCA) antibody

Antigen

Calcitonin-Related Polypeptide alpha (CALCA)
Synonyms CALCA, CALC3, MGC152154, CT, KC, CGRP, CALC1, CGRP1, CGRP-I, MGC126648, CFP1, CGBP, SPP1, PCCX1, PHF18, hCGBP, HsT2645, 2410002I16Rik, 5830420C16Rik, CALC, calcitonin, calca, ci-ct
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Rat (Rattus)
Application
Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Catalog no. ABIN113251
Quantity 0.1 ml  (Variants)
Price 280.00 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

Additional Information
Application Details Alternatives Secondary Antibodies Variants back to top

Characteristics Synonyms: CALCA, CALC1
Alternative name Calcitonin
Swiss-Prot P01258
Immunogen Synthetic peptide corresponding to part of the native molecule conjugated to Keyholelimpet Haemocyanin.
Format Serum
Description Calcitonin is a 32 amino acid peptide hormone synthesized by the parafollicular cells ofthe thyroid. It causes a rapid, but short lived, reduction in serum calcium and phosphateby promoting the incorporation of those ions in the bones. This effect is opposite to that ofparathyroid hormone. Staining for calcitonin may be used for the identification of aspectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasivetumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a finegranular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibitvarying degrees of calcitonin activity.
Specificity Gives positive staining of hormone containing cells in formalin-fixed paraffin sections ofthyroid glands. Species: Human, Rat. Others not tested.

Application Details
Alternatives Secondary Antibodies Variants back to top

Application Notes Immunohistochemistry on paraffin sections (1: 1000 - 1: 4000). Immunohistochemistry on frozen sections (both 30 minutes at 37 C). Immunoflourencence 1: 10 - 1: 40). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Buffer 0.09 % Sodium Azide
Storage Store the antibody at -20 °C. Ship at 2 - 8 °C. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
Research Area Cancer, Growth Factors, Hormones, Cytoskeleton, Microfilaments, Innate Immunity, Chemokines
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies Variants back to top

Alternatives for antigen "Calcitonin-Related Polypeptide alpha (CALCA)", type "Antibodies"
Hosts Rabbit (88), Mouse (12), Goat (7), Sheep (4), Chicken (2), Guinea Pig (2)
Reactivities Human (101), Rat (Rattus) (35), Dog (Canine) (27), Mouse (Murine) (20), Pig (Porcine) (10), Sheep (Ovine) (10), Monkey (7), Rabbit (7), Hamster (6), Cow (Bovine) (3), Mammalian (3), Horse (Equine) (2), Chicken (1), Guinea Pig (1), Reptile (1), Zebrafish (Danio rerio) (1)
Applications Immunofluorescence (IF) (46), Flow Cytometry (FACS) (36), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (33), Immunohistochemistry (Frozen Sections) (IHC (fro)) (21), Radioimmunoassay (RIA) (20), Enzyme Immunoassay (EIA) (17), Western Blotting (WB) (17), ELISA (10), Immunohistochemistry (IHC) (9), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (4), Immunoprecipitation (IP) (4), ELISA (Capture) (2), Immunoelectron Microscopy (IEM) (2), ELISA (Detection) (1)
Conjugates Biotin (6), Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2), RBITC (2)
Epitopes AA 1-32 (6), C-Term (2)