CD72 Molecule (CD72) antibody (FITC)

Details for Product No. ABIN114245
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Antigen
Synonyms LYB2, CD72b
Reactivity
Mouse (Murine)
(64), (30)
Host
Mouse
(79), (17), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
FITC
(16), (13), (12)
Application
Flow Cytometry (FACS)
(66), (20), (20), (13), (10), (4), (3), (1), (1), (1)
Pubmed 3 references available
Catalog no. ABIN114245
Quantity 0.3 mg
Price
808.50 $   Plus shipping costs $45.00
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Clone CT-72-4
Isotype IgG2b
Specificity This monoclonal antibody reacts with an antigen that is expressed on pre B and B cells with either Lyb-2a or Lyb-2b allele. It is also found on some T cell subsets and a small percentage of thymocytes.
Alternative Name CD72
Background CD72 antigen is a member of the type II integral membrane glycoproteins which includes other related cell surface molecules such as the asialoglycoprotein receptors, CD23 and the Kupffer cell receptor. The function of CD72 is unknown but the exposure of B cells to CD72 antibodies activates a variety of signaling pathways and can induce MHC class II expression and B cell proliferation. CD72 antigen is expressed on all cells of B cell lineage with the exception of plasma cells and weakly on human tissue macrophages.
Alternate names: B-Cell marker, B-cell differentiation antigen CD72, Ly-32, Ly32, Lyb-2, Lymphocyte antigen 32
Gene ID 100504743
NCBI Accession XP_003086403.1
UniProt P21855
Research Area Stem Cells, Hematopoietic Progenitors, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow Cytometry: single, dual or three colour, 1g is the maximum amount of antibodyrequired for 10e6 cells, Lesser amounts of antibody may be sufficient, and it isrecommended that the customer determine the optimum amount of antibody for eachapplication. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.1 mg/mL
Buffer PBS, 0.1% Sodium azide and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Supplier Images
anti-CD72 Molecule (CD72) antibody (FITC) Cell source: C57BL/6 spleen cells - Percentage of cells stained above control: 99.7%
Background publications Luo, Van de Velde, von Hoegen et al.: "Ly-1 (CD5), a membrane glycoprotein of mouse T lymphocytes and a subset of B cells, is a natural ligand of the B cell surface protein Lyb-2 (CD72)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 6, pp. 1630-4, 1992 (PubMed).

Robinson, Landolfi, Schäfer et al.: "Biochemical identity of the mouse Ly-19.2 and Ly-32.2 alloantigens with the B cell differentiation antigen Lyb-2/CD72." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 9, pp. 4764-72, 1993 (PubMed).

Schimmel, Kearley, Nijkamp et al.: "Hydrogen adsorption in carbon nanostructures: comparison of nanotubes, fibers, and coals." in: Chemistry (Weinheim an der Bergstrasse, Germany), Vol. 9, Issue 19, pp. 4764-70, 2003 (PubMed).

Hosts (79), (17), (1)
Reactivities (64), (30)
Applications (66), (20), (20), (13), (10), (4), (3), (1), (1), (1)
Conjugates (16), (13), (12)
Epitopes (4), (2), (2), (2), (1), (1)
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