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Details for Product No. ABIN114467

Glycophorin A (MNS Blood Group) (GYPA) antibody

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Antigen
Synonyms CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2, AI853584, GYPA, gpa
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Pubmed 1 reference available
Catalog no. ABIN114467
Quantity 0.5 mL
Price
324.50 $   Plus shipping costs $45.00
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Immunogen Formalin fixed membrane from a Hairy cell leukemia
Clone JC159
Isotype IgG1
Specificity This antibody reacts with glycophorin A in the erythroid cells. It can stain erythroid cells at all stages of development and differentiation. The antibody may be useful in the identification of neoplastic erythroblasts. Cellular Localization: Cell membrane
Purification Supernatant
Alternative Name CD235a / GYPA
Background Glycophorins A (GPA) and B (GPB) are single pass membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors and also binds influenza virus.
Alternate names: GPA, Glycophorin-A, MN sialoglycoprotein, PAS-2, Sialoglycoprotein alpha
Gene ID 2993
NCBI Accession NP_002090.4
UniProt P02724
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Immunohistochemistry on formalin fixed paraffin embedded sections: use a dilution of1: 25-1: 50 in an ABC method (30 minutes at room temperature). Recommended positive control: TonsilOther applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Loken, Shah, Dattilio et al.: "Flow cytometric analysis of human bone marrow: I. Normal erythroid development." in: Blood, Vol. 69, Issue 1, pp. 255-63, 1987 (PubMed).

Alternatives for antigen "Glycophorin A (MNS Blood Group) (GYPA)", type "Antibodies"
Hosts (112), (45), (26), (10)
Reactivities (189), (13), (13)
Applications (113), (52), (46), (34), (26), (20), (14), (13), (11), (7), (5), (5), (4), (1), (1), (1), (1)
Conjugates (29), (19), (9), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (18), (7), (1), (1), (1)
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