CRP antibody

Catalog No. ABIN114518

Product Details anti-CRP Antibody

Target: CRP (C-Reactive Protein (CRP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CRP antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), ELISA (Capture)

Specificity: Recognizes Human CRP. No detectable cross-reaction with Human normal serum proteins. Other species not tested.

Purification: Affinity Chromatography on Protein G

Immunogen: Purified CRP from Human pleural fluid

Clone: 63F4

Isotype: IgG1

Application Details

Application Notes: ELISA. Immunoblot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with Double distillated water is recommended and to adjust the final concentration to 1.0 mg/mL

Concentration: 1.0 mg/mL

Buffer: 0.01 M PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CRP

Target: CRP (C-Reactive Protein (CRP))

Abstract: CRP Products

Synonyms: PTX1 antibody, crp antibody, AI255847 antibody, Aa1249 antibody, Ab1-341 antibody, Ab2-196 antibody, Ac1-114 antibody, Ac1262 antibody, Ac2-069 antibody, Ba2-693 antibody, APCS antibody, 0610010I23Rik antibody, AW743261 antibody, C77570 antibody, CRP2 antibody, CRP4 antibody, Crp antibody, ESP1 antibody, Hlp antibody, CRP5.1 antibody, zgc:152809 antibody, C-reactive protein antibody, C-reactive protein, pentraxin-related antibody, c-reactive protein, pentraxin-related antibody, cysteine rich protein 2 antibody, CRP antibody, crp antibody, Crp antibody, Crip2 antibody, LOC776376 antibody

Background: C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture.Synonyms: C Reactive Protein, PTX1, Pentraxin-related

Gene ID: 1401

NCBI Accession: NP_000558

UniProt: P02741

Pathways: Carbohydrate Homeostasis