CSF3R antibody

Catalog No. ABIN114566

Product Details anti-CSF3R Antibody

Target: CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CSF3R antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects G-CSFR (CD114). Does not cross-react with MBP or BSA (bovine serum albumin).

Purification: Protein G affinity chromatography

Immunogen: Purified recombinant MBP-GCSFR fusion protein

Clone: S-1284

Isotype: IgG2a

Application Details

Application Notes: ELISA. Immunoblotting: Recognizes denatured G-CSFR following SDS-PAGE and blotting of 200 gof cell lysate or following immunoprecipitation with polyclonal antibody followed byimmunoblotting. Western Blot: At an antibody concentration of 1-10 μg/mL will allow visualization of 250 ng/lane of human G-CSFR-MBP.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: In double distilled water to a concentration to 1.00 mg/mL

Buffer: 0.01 M PBS, pH 7.2

Handling Advice: Dilute only prior to immediate use

Storage: 4 °C

Storage Comment: Store the antibody (undiluted) at 2-8 °C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.

Target Details for CSF3R

Target: CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))

Alternative Name: CD114 / CSF3R (CSF3R Products)

Synonyms: CD114 antibody, GCSFR antibody, Cd114 antibody, Csfgr antibody, G-CSF-R antibody, G-CSFR antibody, CSF3R antibody, gcsfr antibody, cd114 antibody, colony stimulating factor 3 receptor antibody, colony stimulating factor 3 receptor (granulocyte) antibody, colony stimulating factor 3 receptor L homeolog antibody, granulocyte colony-stimulating factor receptor antibody, CSF3R antibody, Csf3r antibody, csf3r antibody, csf3r.L antibody, LOC100433338 antibody

Background: The protein encoded by the GCSF Receptor gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, of which three are membrane-bound and the one secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.Synonyms: G-CSF Receptor, G-CSF-R, GCSF Receptor, GCSFR, Granulocyte colony-stimulating factor receptor

Gene ID: 1441

NCBI Accession: NP_000751

UniProt: Q99062