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Cytokeratin 1 (KRT1) (pan) antibody

Details for Product No. ABIN114573, Supplier: Login to see
Antigen
  • EpK
  • cytok
  • cytokeratin
  • epi-keratin
  • epiker
  • xK81
Epitope
pan
49
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
90
18
14
10
9
7
7
5
5
5
5
4
3
3
2
2
2
1
1
1
1
1
1
1
Host
Mouse
93
7
4
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
4
3
2
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
59
45
42
35
29
26
21
18
12
2
2
2
1
1
1
1
1
Supplier
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Immunogen Cytokeratins from human breast carcinoma cell line MCF-7 and detergent insoluble fraction of psoriatic epidermis.
Clone Cocktail
Isotype Cocktail
Purification Supernatant
Alternative Name Cytokeratin (KRT1 Antibody Abstract)
Background This antibody is a cocktail of two different clones, 5D3 andLP53.Synonyms: Cytokeratin pan-reactive, pan Keratin
Research Area Signaling, Cytoskeleton, Cytokeratins, Extracellular Matrix
Pathways
Application Notes Immunohistochemistry on paraffin embedded sections: diluted of 1: 15-1: 50 in an ABCmethod (30 minutes at room temperature)Proteolytic digestion of tissue sections is required prior to immunostaining. Positive Control: Skin
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Moll, Franke, Schiller et al.: "The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells." in: Cell, Vol. 31, Issue 1, pp. 11-24, 1983 (PubMed).

Gatter, Abdulaziz, Beverley et al.: "Use of monoclonal antibodies for the histopathological diagnosis of human malignancy." in: Journal of clinical pathology, Vol. 35, Issue 11, pp. 1253-67, 1983 (PubMed).

Angus, Kiberu, Purvis et al.: "Cytokeratins in cervical dysplasia and neoplasia: a comparative study of immunohistochemical staining using monoclonal antibodies NCL-5D3, CAM 5.2, and PKK1." in: The Journal of pathology, Vol. 155, Issue 1, pp. 71-5, 1988 (PubMed).

Henze, Fengler, Hartmann et al.: "Six-year experience with a comprehensive approach to the treatment of recurrent childhood acute lymphoblastic leukemia (ALL-REZ BFM 85). A relapse study of the BFM group." in: Blood, Vol. 78, Issue 5, pp. 1166-72, 1991 (PubMed).