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Estrogen Receptor 1 (ESR1) antibody

Details for Product No. ABIN114680
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Antigen
Synonyms
ER, ERa, ESR, Estr, ER[a], Estra, Nr3a1, ERalpha, AA420328, AU041214, ER-alpha, ESRA, ESTRR, Era, NR3A1, Esr, RNESTROR, ERALPHA, ACTGP1, ACT1GP1, HY-psi-gamma-AC6, eralpha, zfER[a], ER[b]1, zfER-beta1 ... show more
ER, ERa, ESR, Estr, ER[a], Estra, Nr3a1, ERalpha, AA420328, AU041214, ER-alpha, ESRA, ESTRR, Era, NR3A1, Esr, RNESTROR, ERALPHA, ACTGP1, ACT1GP1, HY-psi-gamma-AC6, eralpha, zfER[a], ER[b]1, zfER-beta1, zfER[b]1, ER[b]2, ER[b]a, zfER[b]2, zfER-beta2, erb, esrb, estrb, nr3a2, ERbeta, er-beta, esr-beta, XER, era, esr, esra, nr3a1, xesr-1, xlERalpha1, xlERalpha2, LOC398733, LOC398734, err1, erra, esrral, erralpha, ESR2, ESRRA, ESR1, esrl1, nr3b1, er, LOC100125507 show less
Reactivity
Human
(615), (258), (144), (56), (39), (26), (13), (11), (3), (2), (1), (1), (1), (1), (1)
Host
Mouse
(493), (164), (7), (2), (2)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(22), (18), (17), (10), (10), (10), (10), (10), (10), (10), (10), (7), (7), (7)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(473), (220), (200), (175), (100), (85), (68), (40), (33), (19), (10), (6), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Pubmed 4 references available
Quantity 1 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN114680
1,204.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Recombinant human estrogen receptor protein.
Clone 1D5
Isotype IgG1
Specificity This antibody is specific to estrogen receptor, which is associated with superior prognosis and a better response to endocrine therapy. Cellular Localization: Nuclear
Purification Supernatant
Alternative Name Estrogen receptor alpha
Background The nuclei of the estrogen receptor positive cells stain very strongly with this antibody, without any staining in the cytoplasm. However, on cryostat sections a positive staining of estrogen receptor in the nucleus as well as cytoplasm can be seen.
Alternate names: ER alpha, ESR, ESR1, Estradiol receptor, NR3A1, Nuclear receptor subfamily 3 group A member 1
Gene ID 2099
NCBI Accession NP_000116.2
UniProt P03372
Research Area Hormones, Receptors
Application Notes Western Blotting: 1: 50 to 1: 100. Immunohistochemistry on frozen and paraffin embedded sections: diluted of 1: 25 to 1: 50 inan ABC method (30 minutes at room temperature)Recommended Positive Control: Breast carcinomaOther applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer 10 mM citrate buffer, pH 6.0 - containing sodium azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Estrogen Receptor 1 (ESR1) antibody Formalin fixed paraffin embedded human breast carcinoma stained with Estrogen Receptor antibody
General Bur, Zimarowski, Schnitt et al.: "Estrogen receptor immunohistochemistry in carcinoma in situ of the breast." in: Cancer, Vol. 69, Issue 5, pp. 1174-81, 1992 (PubMed).

Graham, Jin, Lloyd: "Detection of estrogen receptor in paraffin-embedded sections of breast carcinoma by immunohistochemistry and in situ hybridization." in: The American journal of surgical pathology, Vol. 15, Issue 5, pp. 475-85, 1991 (PubMed).

Pertschuk, Kim, Nayer et al.: "Immunocytochemical estrogen and progestin receptor assays in breast cancer with monoclonal antibodies. Histopathologic, demographic, and biochemical correlations and relationship to endocrine response and survival." in: Cancer, Vol. 66, Issue 8, pp. 1663-70, 1990 (PubMed).

Kumar, Green, Stack et al.: "Functional domains of the human estrogen receptor." in: Cell, Vol. 51, Issue 6, pp. 941-51, 1988 (PubMed).

Hosts (493), (164), (7), (2), (2)
Reactivities (615), (258), (144), (56), (39), (26), (13), (11), (3), (2), (1), (1), (1), (1), (1)
Applications (473), (220), (200), (175), (100), (85), (68), (40), (33), (19), (10), (6), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Conjugates (22), (18), (17), (10), (10), (10), (10), (10), (10), (10), (10), (7), (7), (7)
Epitopes (54), (43), (39), (38), (36), (25), (19), (13), (10), (8), (8), (8), (8), (7), (7), (6), (6), (5), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN114680
1,204.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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