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CCL3 antibody

CCL3 Reactivity: Human EIA Host: Mouse Monoclonal 199 unconjugated
Catalog No. ABIN114725
  • Target See all CCL3 Antibodies
    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
    Reactivity
    • 57
    • 23
    • 19
    • 3
    • 2
    Human
    Host
    • 62
    • 26
    • 2
    • 2
    • 1
    Mouse
    Clonality
    • 69
    • 24
    Monoclonal
    Conjugate
    • 53
    • 13
    • 7
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCL3 antibody is un-conjugated
    Application
    • 66
    • 55
    • 20
    • 18
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts with recombinant MIP1 alpha. Does not show any cross reaction with other human cytokines or growth factors tested such as M-CSF, GM-CSF, IL-7, IL-8, IL-16, IL1 beta, bFGF, TGF beta, EGF, TNF alpha and EPO.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography on Protein G.
    Immunogen
    Purified recombinant Human MIP1 alpha.
    Clone
    199
    Isotype
    IgG2a
    Top Product
    Discover our top product CCL3 Primary Antibody
  • Application Notes
    ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with double distillated water to adjust the final concentration to 1.0 mg/mL.
    Buffer
    0.01 M PBS, pH 7.2 without preservatives.
    Preservative
    Without preservative
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody at -20 °C. Can be shipped at 2 - 8 °C.
  • Target
    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
    Alternative Name
    MIP1 alpha / CCL3 (CCL3 Products)
    Synonyms
    MIP-1alpha antibody, G0S19-1 antibody, LD78ALPHA antibody, MIP-1-alpha antibody, MIP1A antibody, SCYA3 antibody, MIP-1a antibody, Scya3 antibody, AI323804 antibody, LD78alpha antibody, MIP1-(a) antibody, MIP1-alpha antibody, Mip1a antibody, CCL3L1 antibody, CCL3L3 antibody, chemokine (C-C motif) ligand 3 antibody, C-C motif chemokine ligand 3 antibody, CCL3 antibody, Ccl3 antibody
    Background
    Macrophage Inflammatory Protein 1 alpha (MIP1 alpha) and MIP1 beta, two closely related but distinct proteins, were originally co-purified from medium conditioned by a LPS-stimulated murine macrophage cell line. Mature mouse MIP1 alpha shares approximately 77 % and 70 % amino acid identity with human MIP1 alpha and mouse MIP1 beta, respectively. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. Has adhesive effects on lymphocytes. MIP1 alpha can inhibit the proliferation of hematopoietic stem cells in vitro as well as in vivo. A signal transducing receptor, designated the C-C chemokine receptor-1 (C-C CKR-1) with seven transmembrane domains that bind MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities, has been isolated.Synonyms: C-C motif chemokine 3, CCL-3, G0/G1 switch regulatory protein 19-1, G0S19-1 protein, LD78 alpha, MIP-1-alpha, MIP1A, Macrophage Inflammatory Protein 1 alpha, SCYA3, Small-inducible cytokine A3, Tonsillar lymphocyte LD78 alpha protein
    Gene ID
    6348
    NCBI Accession
    NP_002974
    UniProt
    P10147
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Autophagy
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