Cadherin (C-Term) antibody

Details for Product No. ABIN114745
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Antigen
Synonyms PCDH10, OLpcad, cadherin, ci-cadherin
Epitope
C-Term
(18), (7), (1), (1), (1)
Reactivity
Human, Mammalian
(28), (12), (8), (6), (5), (4), (3), (3), (2), (2), (2)
Host
Mouse
(24), (10)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(22), (16), (6), (6), (4), (3), (3), (1)
Pubmed 3 references available
Catalog no. ABIN114745
Quantity 0.5 mL
Price
324.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days

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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide corresponding to the C-terminal amino acids of chicken N-Cadherin with extra N-terminal lysine residue.
Clone CH-19
Isotype IgG1
Specificity This antibody reacts with pan cadherin with a distinct 135 kD band in a wide variety of tissues. Cellular Localization: Cell membrane
Purification Supernatant
Background Cadherins are members of a multigene family of single chain glycoprotein receptors mediating Ca2+ dependent cell-cell adhesion.
Alternate names: pan Cadherin
Research Area Extracellular Matrix, Signaling, Cytoskeleton
Application Notes Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted to a titer of1: 25-1: 50 in an ABC method (30 minutes at room temperature)Recommended Positive Control: TonsilProteolytic treatment prior to immunostaining is required. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer containing sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
General Geiger, Volberg, Ginsberg et al.: "Broad spectrum pan-cadherin antibodies, reactive with the C-terminal 24 amino acid residues of N-cadherin." in: Journal of cell science, Vol. 97 ( Pt 4), pp. 607-14, 1991 (PubMed).

Takeichi: "The cadherins: cell-cell adhesion molecules controlling animal morphogenesis." in: Development (Cambridge, England), Vol. 102, Issue 4, pp. 639-55, 1988 (PubMed).

Grunwald: "The structural and functional analysis of cadherin calcium-dependent cell adhesion molecules." in: Current opinion in cell biology, Vol. 5, Issue 5, pp. 797-805, 1993 (PubMed).

Hosts (24), (10)
Reactivities (28), (12), (8), (6), (5), (4), (3), (3), (2), (2), (2)
Applications (22), (16), (6), (6), (4), (3), (3), (1)
Conjugates (1)
Epitopes (18), (7), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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