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Antibody
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anti-Proopiomelanocortin POMC
Proopiomelanocortin (POMC) antibody
| Antigen |
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| Synonyms |
MSH, ACTH, pomc, SI:bZ36D5.1, SI:bZ36D5.4, si:bz36d5.2, POMC, LPH, NPP, POC, CLIP |
| Clonality |
Monoclonal (AH26) |
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Host
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Reactivity
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Application
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 Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (35), Immunohistochemistry (Frozen Sections) (IHC (fro)) (32), Western Blotting (WB) (23), Enzyme Immunoassay (EIA) (21), Immunofluorescence (IF) (18), ELISA (15), Immunohistochemistry (IHC) (11), Radioimmunoassay (RIA) (5), ELISA (Detection) (4), Immunoprecipitation (IP) (3), Immunocytochemistry (ICC) (2), Dot Blot (Dot) (1)
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| Catalog no. |
ABIN114763 |
| Quantity |
1 ml (Variants) |
| Price |
450.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: Corticotropin, Adrenocorticotropic hormone, ACTH
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Alternative name
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Adrenocorticotropic Hormone (ACTH)
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Swiss-Prot
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P01189
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Immunogen
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BALB/C mice were injected with a synthetic peptide corresponding to amino acids 1-24from the N-terminal of human ACTH.
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Format
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Supernatant
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Isotype
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IgG1 (Matching secondary antibodies)
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Clone
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AH26
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Description
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ACTH occurs in cells of the anterior pituitary and in neurons in brain. It regulates thecorticosteroid production in the adrenal cortex. Beta endorphin and Met enkephalin areendogenous opiates. MSH (melanocyte stimulating hormone) increases the pigmentationof skin by increasing melanin production in melanocytes.
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Specificity
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This antibody is specific to an epitope on the N-terminus of ACTH. Cellular Localization: CytoplasmicSpecies: Human. Others not tested.
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Application Notes
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Immunohistochemistry on paraffin embedded sections: diluted of 1: 50-1: 100 in an ABCmethod (30 minutes at room temperature)Recommended Positive Control: PituitaryOther applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Buffer
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containing sodium azide as preservative.
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Storage
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Research Area
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Hormones
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Restrictions
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For Research Use only
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Alternatives for antigen "Proopiomelanocortin (POMC)", type "Antibodies"
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Hosts
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Mouse (42), Rabbit (36), Goat (6), Guinea Pig (2)
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Reactivities
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Human (73), Rat (Rattus) (20), Mouse (Murine) (9), Sheep (Ovine) (4), Pig (Porcine) (3), Cow (Bovine) (2), All Species (1), Dog (Canine) (1)
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Applications
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (35), Immunohistochemistry (Frozen Sections) (IHC (fro)) (32), Western Blotting (WB) (23), Enzyme Immunoassay (EIA) (21), Immunofluorescence (IF) (18), ELISA (15), Immunohistochemistry (IHC) (11), Radioimmunoassay (RIA) (5), ELISA (Detection) (4), Immunoprecipitation (IP) (3), Immunocytochemistry (ICC) (2), Dot Blot (Dot) (1)
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Conjugates
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FITC (1)
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Epitopes
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C-Term (5), N-Term (5), AA 1-24 (2), AA 1-39 (2), N-Term AA 1-24 (1)
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